Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Torcetrapib [USAN:INN]
RN: 262352-17-0
UNII: 4N4457MV2U
InChIKey: CMSGWTNRGKRWGS-NQIIRXRSSA-N

Note

  • Inhibits cholesteryl ester transfer protein; modest increase in blood pressure led to reevaluation.

Molecular Formula

  • C26-H25-F9-N2-O4

Molecular Weight

  • 600.4755
 

Classification Codes

  • Anticholesteremic Agents
  • Antimetabolites
  • Heart Disease (Cholesteryl Ester Transfer Protein Inhibitor)
  • Hypolipidemic Agents
  • Lipid Regulating Agents
  • Treatment of Atherosclerosis
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Torcetrapib
  • Torcetrapib [USAN:INN]

Synonyms

  • (2R,4S)-4-((3,5-Bis-trifluoromethylbenzyl)methoxycarbonylamino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid ethyl ester
  • 1(2H)-Quinolinecarboxylic acid, 4-(((3,5-bis(trifluoromethyl)phenyl)methyl) (methoxycarbonyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, ethyl ester, (2R,4S)-
  • CP 529414
  • CP-529,414
  • CP-529414
  • Ethyl (2R,4S)-4-((3,5-bis(trifluoromethyl)benzyl)(methoxycarbonyl)amino)-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate
  • Torcetrapib
  • UNII-4N4457MV2U

Systematic Names

  • 1(2H)-Quinolinecarboxylic acid, 4-(((3,5-bis(trifluoromethyl)phenyl)methyl) (methoxycarbonyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, ethyl ester, (2R,4S)-
  • Ethyl (2R,4S)-4-((3,5-bis(trifluoromethyl)benzyl)(methoxycarbonyl)amino)-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate

Registry Numbers

CAS Registry Number

  • 262352-17-0

FDA UNII

  • 4N4457MV2U

System Generated Number

  • 0262352170

Structure Descriptors

InChI

1S/C26H25F9N2O4/c1-4-18-12-21(19-11-15(24(27,28)29)6-7-20(19)37(18)23(39)41-5-2)36(22(38)40-3)13-14-8-16(25(30,31)32)10-17(9-14)26(33,34)35/h6-11,18,21H,4-5,12-13H2,1-3H3/t18-,21+/m1/s1

InChIKey

CMSGWTNRGKRWGS-NQIIRXRSSA-N

Smiles

N1([C@@H](C[C@@H](c2cc(ccc12)C(F)(F)F)N(C(=O)OC)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)CC)C(=O)OCC