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Substance Name: OI 77
RN: 26244-92-8
InChIKey: IXQFTUGOISOXOF-UHFFFAOYSA-N

Note

  • Tricyclic antidepressant, more stimulant than imipramine in clinical trials.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H18-N2-O.Cl-H

Molecular Weight

  • 302.803
 
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Names and Synonyms

Name of Substance

  • OI 77

Synonyms

  • 5-Methylaminoacetyl-6-methyl-5,6-dihydro-phenanthridine-hyrochloride
  • OI 77

Systematic Names

  • 5,6-Dihydro-6-methyl-5-((methylamino)acetyl)phenanthridine
  • Phenanthridine, 5,6-dihydro-5-methylaminoacetyl-6-methyl-, hydrochloride
  • Phenanthridine, 5,6-dihydro-6-methyl-5-((methylamino)acetyl)-, monohydrochloride (9CI)
  • Phenanthridine, 5,6-dihydro-6-methyl-5-(N-methylglycyl)-, monohydrochloride (8CI)

Registry Numbers

CAS Registry Number

  • 26244-92-8

System Generated Number

  • 0026244928

Molecular Formulas

Molecular Formula

  • C17-H18-N2-O.Cl-H

Molecular Formula Fragments

  • C17-H18-N2-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C17H18N2O.ClH/c1-12-13-7-3-4-8-14(13)15-9-5-6-10-16(15)19(12)17(20)11-18-2;/h3-10,12,18H,11H2,1-2H3;1H

InChIKey

IXQFTUGOISOXOF-UHFFFAOYSA-N

Smiles

c1cccc2N([C@@H](c3ccccc3c12)C)C(=O)CNC.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 150mg/kg (150mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 1295, 1973.
mouse LD50 oral 190mg/kg (190mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 1295, 1973.