Skip Navigation
ChemIDplus A TOXNET DATABASE Lite•Browse•Advanced

Substance Name: Indoramin [USAN:INN:BAN]
RN: 26844-12-2
UNII: 0Z802HMY7H
InChIKey: JXZZEXZZKAWDSP-UHFFFAOYSA-N

Note

  • An alpha-1 adrenergic antagonist that is commonly used as an antihypertensive agent.

Molecular Formula

  • C22-H25-N3-O

Molecular Weight

  • 347.4595
 

Classification Codes

  • Adrenergic Agents
  • Adrenergic alpha-1 Receptor Antagonists
  • Adrenergic alpha-Antagonists
  • Adrenergic Antagonists
  • Antihypertensive
  • Antihypertensive Agents
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Neurotransmitter Agents
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Indoramin
  • Indoramin [USAN:INN:BAN]

MeSH Heading

  • Indoramin

Synonyms

  • 3-(2-(4-Benzamidopiperid-1-yl)ethyl)indole
  • 5-22-10-00116 (Beilstein Handbook Reference)
  • Benzamide, N-(1-(2-(1H-indol-3-yl)ethyl)-4-piperidinyl)-
  • BRN 0494035
  • EINECS 248-041-5
  • Indoramin
  • Indoramina
  • Indoramina [INN-Spanish]
  • Indoramine
  • Indoramine [INN-French]
  • Indoraminum
  • Indoraminum [INN-Latin]
  • N-(1-(2-(1H-Indol-3-yl)ethyl)-4-piperidinyl)benzamide
  • N-(1-(2-Indol-3-ylethyl)-4-piperidyl)benzamide
  • UNII-0Z802HMY7H
  • WY 21901

Systematic Names

  • Benzamide, N-(1-(2-(1H-indol-3-yl)ethyl)-4-piperidinyl)-
  • Benzamide, N-(1-(2-indol-3-ylethyl)-4-piperidyl)-
  • Indoramin

Registry Numbers

CAS Registry Number

  • 26844-12-2

FDA UNII

  • 0Z802HMY7H

System Generated Number

  • 0026844122

Structure Descriptors

InChI

1S/C22H25N3O/c26-22(17-6-2-1-3-7-17)24-19-11-14-25(15-12-19)13-10-18-16-23-21-9-5-4-8-20(18)21/h1-9,16,19,23H,10-15H2,(H,24,26)

InChIKey

JXZZEXZZKAWDSP-UHFFFAOYSA-N

Smiles

c1ccc(cc1)C(=O)NC2CCN(CC2)CCc3c[nH]c4c3cccc4

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 400mg/kg (400mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Journal of Medicinal Chemistry. Vol. 14, Pg. 1054, 1971.
rat LD50 intraperitoneal 500mg/kg (500mg/kg)   Journal of Medicinal Chemistry. Vol. 14, Pg. 1054, 1971.
rat LD50 oral 1800mg/kg (1800mg/kg)   Journal of Medicinal Chemistry. Vol. 14, Pg. 1054, 1971.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 209 deg C   EXP
log P (octanol-water) 3.600 (none)   EST
Atmospheric OH Rate Constant 3.21E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.