Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Glutathione disulfide
RN: 27025-41-8
UNII: ULW86O013H
InChIKey: YPZRWBKMTBYPTK-BJDJZHNGSA-N

Note

  • A GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.

Molecular Formula

  • C20-H32-N6-O12-S2

Molecular Weight

  • 612.635
 

Classification Code

  • Drug / Therapeutic Agent
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • Glutathione disulfide

Name of Substance

  • Glutathione disulfide
  • Oxiglutatione [INN]

MeSH Heading

  • Glutathione disulfide

Synonyms

  • CCRIS 780
  • EINECS 248-170-7
  • Glutamine, N,N'-(dithiobis(1-((carboxymethyl)carbamoyl)ethylene))di-, L-
  • Glutathione disulfide
  • Glutathione disulphide
  • Glutathione-ssg
  • Glutathone disulfide
  • GSSG
  • L-Oxidized glutathione
  • N,N'-(Dithiobis((R)-1-((carboxymethyl)carbamoyl)ethylene))di-L-glutamine
  • N-(N-gamma-Glutamyl-cysteinyl)glycine-(2,2)-disulfide
  • Oxidized glutathione
  • Oxiglutationa
  • Oxiglutationa [INN-Spanish]
  • Oxiglutatione
  • Oxiglutationum
  • Oxiglutationum [INN-Latin]
  • Oxigluthione
  • S,S'-Ethylenebis(glutathione)
  • UNII-ULW86O013H

Systematic Names

  • Bi(glutathion-S-yl)
  • Bis(gamma-glutamyl-L-cysteinylglycine) disulfide
  • Glutathione, oxidized
  • Glycine, L-gamma-glutamyl-L-cysteinyl-, (2,2')-disulfide
  • Glycine, L-gamma-glutamyl-L-cysteinyl-, bimol. (2.fwdarw.2')-disulfide
  • N,N'-(Dithiobis((R)-1-((carboxymethyl)carbamoyl)ethylene))di-L-glutamine

Registry Numbers

CAS Registry Number

  • 27025-41-8

FDA UNII

  • ULW86O013H

Other Registry Numbers

  • 10421-65-5
  • 121-24-4

System Generated Number

  • 0027025418

Structure Descriptors

InChI

1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1

InChIKey

YPZRWBKMTBYPTK-BJDJZHNGSA-N

Smiles

C([C@H](CSSC[C@@H](C(NCC(=O)O)=O)NC(=O)CC[C@@H](C(=O)O)N)NC(=O)CC[C@@H](C(=O)O)N)(NCC(=O)O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous > 2gm/kg (2000mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.
mouse LD50 oral > 5gm/kg (5000mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.
mouse LD50 subcutaneous > 2gm/kg (2000mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.
rat LD50 intravenous > 2gm/kg (2000mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.
rat LD50 oral > 5gm/kg (5000mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.
rat LD50 subcutaneous > 2gm/kg (2000mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.