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Substance Name: Amphetamine hydrochloride
RN: 2706-50-5
UNII: 70DMY940ZG
InChIKey: SEVKYLYIYIKRSW-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C9-H13-N.Cl-H

Molecular Weight

  • 171.6696
 
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Names and Synonyms

Results Name

  • Amphetamine hydrochloride

Name of Substance

  • Amphetamine hydrochloride

Synonyms

  • (+-)-alpha-Methylphenethylamine hydrochloride
  • (+-)-Amphetamine hydrochloride
  • 1-Phenyl-2-propylamine hydrochloride
  • alpha-Methylbenzeneethanamine hydrochloride
  • alpha-Methylphenethylamine hydrochloride
  • Amphetamine HCl
  • Amphetamine hydrochloride
  • beta-Phenylisopropylamine hydrochloride
  • dl-alpha-Methyl-phenethylamine hydrochloride
  • dl-Amphetamine hydrochloride
  • dl-beta-Phenylisopropylamine hydrochloride
  • Psychedrine
  • Psychedrine hydrochloride
  • UNII-70DMY940ZG

Systematic Names

  • Benzeneethanamine, alpha-methyl-, hydrochloride
  • Benzeneethanamine, alpha-methyl-, hydrochloride, (+-)-
  • Phenethylamine, alpha-methyl-, hydrochloride, (+-)-

Registry Numbers

CAS Registry Number

  • 2706-50-5

FDA UNII

  • 70DMY940ZG

Other Registry Numbers

  • 28841-71-6
  • 405-41-4

System Generated Number

  • 0002706505

Molecular Formulas

Molecular Formula

  • C9-H13-N.Cl-H

Molecular Formula Fragments

  • C9-H13-N
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C9H13N.ClH/c1-8(10)7-9-5-3-2-4-6-9;/h2-6,8H,7,10H2,1H3;1H

InChIKey

SEVKYLYIYIKRSW-UHFFFAOYSA-N

Smiles

Cl.CC(N)Cc1ccccc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo subcutaneous 52mg/kg (52mg/kg) BEHAVIORAL: TREMOR

SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 47, Pg. 339, 1933.
human TDLo subcutaneous 714ug/kg (0.714mg/kg) VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION JAMA, Journal of the American Medical Association. Vol. 94, Pg. 790, 1930.
mouse LD50 intraperitoneal 40mg/kg (40mg/kg) VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Journal of Medicinal Chemistry. Vol. 8, Pg. 100, 1965.
mouse LD50 intraperitoneal 120mg/kg (120mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Journal of Physiology. Vol. 98, Pg. 424, 1940.
mouse LD50 intravenous 8400ug/kg (8.4mg/kg)   Collection of Czechoslovak Chemical Communications. Vol. 39, Pg. 2819, 1974.
mouse LD50 oral 45mg/kg (45mg/kg)   Journal of the American Chemical Society. Vol. 63, Pg. 602, 1941.
mouse LD50 oral 45mg/kg (45mg/kg)   Journal of the American Chemical Society. Vol. 64, Pg. 533, 1942.
mouse LD50 subcutaneous 42mg/kg (42mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 280, 1946.
rabbit LD50 intramuscular 10mg/kg (10mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 284, 1946.
rabbit LD50 intravenous 10mg/kg (10mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 284, 1946.
rabbit LD50 intravenous 15mg/kg (15mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 79, Pg. 187, 1943.
rabbit LD50 subcutaneous 11mg/kg (11mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 284, 1946.
rat LD50 intraperitoneal 30mg/kg (30mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 284, 1946.
rat LDLo subcutaneous 25mg/kg (25mg/kg)   Journal of the American Chemical Society. Vol. 53, Pg. 1875, 1931.