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Substance Name: 1H-Pyrazino(1,2-a)quinoline, 2,3,4,4a,5,6-hexahydro-3-(2-(p-fluorobenzoyl)ethyl)-, dihydrochloride
RN: 27114-12-1
InChIKey: QXOWEHJVUGQSBP-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C21-H23-F-N2-O.2Cl-H

Molecular Weight

  • 411.345
 
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Names and Synonyms

Synonym

  • NSC 147865

Systematic Names

  • 1-Propanone, 1-(4-fluorophenyl)-3-(1,2,4,4a,5,6-hexahydro-3H-pyrazino(1,2-a)quinolin-3-yl)-, dihydrochloride (9CI)
  • 1H-Pyrazino(1,2-a)quinoline, 2,3,4,4a,5,6-hexahydro-3-(2-(p-fluorobenzoyl)ethyl)-, dihydrochloride
  • Propiophenone, 4'-fluoro-3-(1,2,4,4a,5,6-hexahydro-3H-pyrazino(1,2-a)quinolin-3-yl)-, dihydrochloride (8CI)

Registry Numbers

CAS Registry Number

  • 27114-12-1

System Generated Number

  • 0027114121

Molecular Formulas

Molecular Formula

  • C21-H23-F-N2-O.2Cl-H

Molecular Formula Fragments

  • C21-H23-F-N2-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C21H23FN2O.2ClH/c22-18-8-5-17(6-9-18)21(25)11-12-23-13-14-24-19(15-23)10-7-16-3-1-2-4-20(16)24;;/h1-6,8-9,19H,7,10-15H2;2*1H

InChIKey

QXOWEHJVUGQSBP-UHFFFAOYSA-N

Smiles

N12c3c(cccc3)CC[C@@H]1C[N@@](CC2)CCC(c1ccc(cc1)F)=O.Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 200mg/kg (200mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Journal of Medicinal Chemistry. Vol. 13, Pg. 516, 1970.