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Substance Name: Tramadol [INN:BAN]
RN: 27203-92-5
UNII: 39J1LGJ30J
InChIKey: TVYLLZQTGLZFBW-ZBFHGGJFSA-N
Note
- A narcotic analgesic proposed for severe pain. It may be habituating.
Molecular Formula
- C16-H25-N-O2
Molecular Weight
- 263.3785
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Analgesics
- Analgesics, Opioid
- Central Nervous System Agents
- Central Nervous System Depressants
- Drug / Therapeutic Agent
- Human Data
- Narcotics
- Peripheral Nervous System Agents
- Sensory System Agents
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Names and Synonyms
Results Name
- Tramadol [INN:BAN]
Name of Substance
- Tramadol
- Tramadol [INN:BAN]
MeSH Heading
- Tramadol
Synonyms
- (+-)-Tramadol
- Biomadol
- CG 315E
- cis-Tramadol
- Contramid
- Cyclohexanol, 2-((dimethylamino)methyl)-1-(m-methoxyphenyl)-
- E 265
- EINECS 248-319-6
- HSDB 7047
- Labesfal
- Racemic tramadol
- Ralivia ER
- Ralivia flashtab
- Ryzolt
- Tiparol
- Tradolan
- Tradonal odis
- Tramadis
- Tramadol
- Tramadol Contramid
- Tramadolum
- Tramadolum [INN-Latin]
- Tramadon
- Tramaliv
- Trapidol
- U 26255A
- Ultram
- UNII-39J1LGJ30J
- Zytram
Systematic Names
- Cyclohexanol, 2-((dimethylamino)-1-(3-methoxyphenyl)-, cis-(+-)-
- Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, cis-(+-)-
- Tramadol
Registry Numbers
CAS Registry Number
- 27203-92-5
FDA UNII
- 39J1LGJ30J
Other Registry Numbers
- 113683-92-4
- 73806-46-9
System Generated Number
- 0027203925
Structure Descriptors
InChI
1S/C16H25NO2/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3/t14-,16+/m1/s1InChIKey
TVYLLZQTGLZFBW-ZBFHGGJFSA-NSmiles
CN(C)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| child | TDLo | intravenous | 4032ug/kg (4.032mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Southern Medical Journal. Vol. 90, Pg. 826, 1997. |
| rat | LD50 | intraperitoneal | 150mg/kg (150mg/kg) | European Patent Application. Vol. #0047990, | |
| rat | LD50 | oral | 228mg/kg (228mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. | |
| rat | LD50 | subcutaneous | 286mg/kg (286mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. | |
| women | TDLo | oral | 16mg/kg/4D-I (16mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: EUPHORIA BEHAVIORAL: WAKEFULNESS | American Journal of Psychiatry. Vol. 154, Pg. 1624, 1997. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| log P (octanol-water) | 3.010 | (none) | EST | |
| Atmospheric OH Rate Constant | 1.47E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.