Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Oxisuran [USAN:INN]
RN: 27302-90-5
UNII: NJM3553DH2
InChIKey: DSWLRNLRVBAVFC-UHFFFAOYSA-N

Note

  • Proposed antineoplastic & immunosuppressive agent.

Molecular Formula

  • C8-H9-N-O2-S

Molecular Weight

  • 183.2301
 

Classification Codes

  • Antineoplastic
  • Drug / Therapeutic Agent
  • Tumor Data
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Oxisuran
  • Oxisuran [USAN:INN]

Synonyms

  • (Methylsulfinyl)methyl 2-pyridyl ketone
  • 2-((Methylsulfinyl)acetyl)pyridine
  • 5-21-12-00151 (Beilstein Handbook Reference)
  • BRN 1526159
  • CCRIS 489
  • Ismisupren
  • NSC 356716
  • Oxisuran
  • Oxisurano
  • Oxisurano [INN-Spanish]
  • Oxisuranum
  • Oxisuranum [INN-Latin]
  • Pyridine, 2-((methylsulfinyl)acetyl)-
  • UNII-NJM3553DH2
  • W 6495

Systematic Names

  • Ethanone, 2-(methylsulfinyl)-1-(2-pyridinyl)-
  • Ketone, (methylsulfinyl)methyl 2-pyridyl (8CI)
  • Oxisuran
  • Pyridine, 2-((methylsulfinyl)acetyl)-

Registry Numbers

CAS Registry Number

  • 27302-90-5

FDA UNII

  • NJM3553DH2

System Generated Number

  • 0027302905

Structure Descriptors

InChI

1S/C8H9NO2S/c1-12(11)6-8(10)7-4-2-3-5-9-7/h2-5H,6H2,1H3

InChIKey

DSWLRNLRVBAVFC-UHFFFAOYSA-N

Smiles

c1(C(C[S@@](C)=O)=O)ccccn1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 5gm/kg (5000mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Toxicology and Applied Pharmacology. Vol. 36, Pg. 49, 1976.
mouse LD50 intravenous 2510mg/kg (2510mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: ATAXIA
Toxicology and Applied Pharmacology. Vol. 36, Pg. 49, 1976.
mouse LD50 oral 5280mg/kg (5280mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
Toxicology and Applied Pharmacology. Vol. 36, Pg. 49, 1976.
rabbit LD50 oral 6610mg/kg (6610mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: ATAXIA
Toxicology and Applied Pharmacology. Vol. 36, Pg. 49, 1976.
rat LD50 intravenous 1800mg/kg (1800mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: ATAXIA
Toxicology and Applied Pharmacology. Vol. 36, Pg. 49, 1976.
rat LD50 oral 6550mg/kg (6550mg/kg) BEHAVIORAL: ATAXIA

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Toxicology and Applied Pharmacology. Vol. 36, Pg. 49, 1976.