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Substance Name: Troleandomycin [USAN:USP:INN:BAN]
RN: 2751-09-9
UNII: C4DZ64560D
InChIKey: LQCLVBQBTUVCEQ-QTFUVMRISA-N
Note
- A macrolide antibiotic that is similar to ERYTHROMYCIN.
Molecular Formula
- C41-H67-N-O15
Molecular Weight
- 813.9723
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antibacterial
- Drug / Therapeutic Agent
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Links to Resources
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Names and Synonyms
Name of Substance
- Troleandomycin
- Troleandomycin [USAN:USP:INN:BAN]
MeSH Heading
- Troleandomycin
Synonyms
- AI3-50166
- Aovine
- Cyclamycin
- EINECS 220-392-9
- Evramicina
- Matromicina
- Matromycin T
- Micotil
- NSC 108166
- Oleandocetine
- Oleandomycin triacetate
- Oleandomycin triacetyl ester
- Oleandomycin, triacetate (ester)
- Oleandomycin, triacetyl-
- T.A.O.
- TAO
- Tao (VAN)
- Treis-Micina
- Treolmicina
- Triacetyl ester of oleandomycin
- Triacetyloleandomycin
- Triacetyloleandomycinum
- Tribiocillina
- Triocetin
- Triolan
- Troleandomicina
- Troleandomicina [INN-Spanish]
- Troleandomycin
- Troleandomycine
- Troleandomycine [INN-French]
- Troleandomycinum
- Troleandomycinum [INN-Latin]
- UNII-C4DZ64560D
- Viamicina
- WY 651
- Wytrion
Systematic Names
- Oleandomycin, triacetate (ester)
- Troleandomycin
Registry Numbers
CAS Registry Number
- 2751-09-9
FDA UNII
- C4DZ64560D
System Generated Number
- 0002751099
Structure Descriptors
InChI
1S/C41H67NO15/c1-19-17-41(18-49-41)38(46)23(5)34(53-27(9)43)21(3)25(7)52-39(47)24(6)35(56-32-16-31(48-14)36(26(8)51-32)54-28(10)44)22(4)33(19)57-40-37(55-29(11)45)30(42(12)13)15-20(2)50-40/h19-26,30-37,40H,15-18H2,1-14H3/t19-,20+,21-,22+,23+,24+,25+,26-,30-,31-,32-,33-,34-,35-,36-,37+,40-,41+/m0/s1InChIKey
LQCLVBQBTUVCEQ-QTFUVMRISA-NSmiles
CO[C@H]1C[C@H](O[C@H]2[C@H](C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intravenous | 198mg/kg (198mg/kg) | Drugs in Japan Vol. 6, Pg. 514, 1982. | |
mouse | LD50 | oral | > 5gm/kg (5000mg/kg) | Drugs in Japan Vol. 6, Pg. 515, 1982. | |
rat | LD50 | intravenous | 117mg/kg (117mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA BEHAVIORAL: TREMOR | Antibiotics and Chemotherapy Vol. 8, Pg. 528, 1958. |
rat | LDLo | oral | > 5gm/kg (5000mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Antibiotics and Chemotherapy Vol. 8, Pg. 528, 1958. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
log P (octanol-water) | 2.540 | (none) | EST | |
Atmospheric OH Rate Constant | 2.46E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.