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Substance Name: Etidronic acid [USAN:INN:BAN]
RN: 2809-21-4
UNII: M2F465ROXU
InChIKey: DBVJJBKOTRCVKF-UHFFFAOYSA-N

Note

  • A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.

Molecular Formula

  • C2-H8-O7-P2

Molecular Weight

  • 206.0262
 

Classification Codes

  • Bone Density Conservation Agents
  • Regulator (Calcium)
  • Reproductive Effect

Names and Synonyms

Name of Substance

  • (1-Hydroxyethylidene)bisphosphonic acid
  • 1-Hydroxy-1,1-diphosphonoethane
  • Etidronic acid
  • Etidronic acid [USAN:INN:BAN]
  • Phosphonic acid, (1-hydroxyethylidene)bis-

MeSH Heading

  • Etidronic acid

Synonyms

  • (1-Hydroxyethylene)diphosphonic acid
  • (1-Hydroxyethylidene)bis(phosphonic acid)
  • (1-Hydroxyethylidene)diphoshonic acid
  • (1-Hydroxyethylidene)diphosphonic acid
  • (Hydroxyethylidene)diphosphonic acid
  • 0-02-00-00171 (Beilstein Handbook Reference)
  • 1,1,1-Ethanetriol diphosphonate
  • 1-Hydroxy-1,1-diphosphonoethane
  • 1-Hydroxyethane-1,1-bisphosphonic acid
  • 1-Hydroxyethane-1,1-diphosphonate
  • 1-Hydroxyethane-1,1-diphosphonic acid
  • 1-Hydroxyethanediphosphonic acid
  • 1-Hydroxyethylidene-1,1-biphosphonate
  • 1-Hydroxyethylidene-1,1-bisphosphonate
  • 1-Hydroxyethylidene-1,1-diphosphonic acid
  • 1000SL
  • Acetodiphosphonic acid
  • Acide etidronique
  • Acide etidronique [INN-French]
  • Acido etidronico
  • Acido etidronico [INN-Spanish]
  • Acidum etidronicum
  • Acidum etidronicum [INN-Latin]
  • BRN 1789291
  • Dequest 2010
  • Dequest 2015
  • Dequest Z 010
  • Diphosphonate (base)
  • EC 220-552-8
  • EHDP
  • EINECS 220-552-8
  • Ethane-1-hydroxy-1,1-diphosphonate
  • Ethane-1-hydroxy-1,1-diphosphonic acid
  • Etidronate
  • Etidronic acid
  • Etidronsaeure
  • Ferrofos 510
  • HEDP
  • HSDB 5898
  • Hydroxyethane-1,1-diphosphonic acid
  • Hydroxyethanediphosphonic acid
  • NSC 227995
  • Oxyethylidenediphosphonic acid
  • Phosphonic acid, (1-hydroxyethylidene)bis-
  • Phosphonic acid, (1-hydroxyethylidene)di-
  • Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester
  • RP 61
  • Turpinal SL
  • UNII-M2F465ROXU

Systematic Names

  • Etidronic acid
  • Phosphonic acid, (1-hydroxyethylidene)bis-
  • Phosphonic acid, (1-hydroxyethylidene)di-
  • Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-

Superlist Names

  • 1-Hydroxyethylidene-1,1-diphosphonic acid
  • Etidronic acid
  • Phosphonic acid, (1-hydroxyethylidene)di-

Registry Numbers

CAS Registry Number

  • 2809-21-4

FDA UNII

  • M2F465ROXU

Other Registry Numbers

  • 100511-44-2
  • 103736-66-9
  • 106908-76-3
  • 129130-42-3
  • 138360-84-6
  • 192526-55-9
  • 303177-33-5
  • 51888-66-5
  • 66216-98-6
  • 83047-25-0
  • 853028-38-3
  • 85985-26-8
  • 86159-18-4

Related Registry Number

  • 14860-53-8 (tetra-potassium salt)

System Generated Number

  • 0002809214

Structure Descriptors

InChI

1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9)

InChIKey

DBVJJBKOTRCVKF-UHFFFAOYSA-N

Smiles

CC(O)(P(=O)(O)O)P(=O)(O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 1800mg/kg (1800mg/kg)   Angewandte Chemie, International Edition in English. Vol. 14, Pg. 94, 1975.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) -0.810 (none)   EST
Water Solubility 6.90E+05 mg/L 20 EXP
Atmospheric OH Rate Constant 1.22E-12 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.