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Substance Name: Antimony potassium tartrate [USP]
RN: 28300-74-5
UNII: DL6OZ476V3
InChIKey: WBTCZEPSIIFINA-MSFWTACDSA-J

Note

  • A schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.

Molecular Formulas

  • C4-H4-K-O7-Sb
  • C4-H4-K2-O7-Sb
  • C8-H4-K2-O12-Sb2.3H2-O
  • C8-H4-O12-Sb2.3H2-O.2K

Molecular Weight

  • 667.868
 

Classification Codes

Classification Codes

  • Anthelmintics
  • Anti-Infective Agents
  • Antiparasitic Agents
  • Antiplatyhelmintic Agents
  • Antischistosomal
  • Drug / Therapeutic Agent
  • Human Data
  • Mutation Data
  • Schistosomicides
  • Tumor Data

Superlist Classification Code

  • Reportable Quantity (RQ) = 100 lb
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Names and Synonyms

Name of Substance

  • Antimonate (2-), bis(mu-(2,3-dihydroxybutanedioato(4-)-O1,O2,O3,O4))di-, dipotassium, trihydrate, stereoisomer
  • Antimony potassium tartrate
  • Antimony potassium tartrate [USP]
  • Tartar emetic

MeSH Heading

  • Antimony potassium tartrate

Synonyms

  • AI3-19187
  • Antimonate(2)-, bis(mu-tartrato(4-))di-, dipotassium, trihydrate
  • Antimonate(2-), bis(mu-(2,3-dihydroxybutanedioato(4-)-O(sup 1),O(sup 2):O(sup 3),O(sup 4)))-di-, dipotassium, trihydrate, stereoisomer
  • Antimony potassium tartrate
  • Antimonyl potassium tartrate
  • Caswell No. 053
  • CCRIS 1380
  • Dipotassium bis(mu-(L-(+)-tartrato(4-)))diantimonate(2-) trihydrate
  • Emetique
  • Emetique [French]
  • ENT 50,434
  • EPA Pesticide Chemical Code 006201
  • HSDB 1428
  • Potassium antimony tartrate
  • Potassium antimonyl D-tartrate
  • Potassium antimonyl tartrate
  • Potassium antimonyltartrate
  • Tartar emetic
  • Tartaric acid, antimony potassium salt
  • Tartarized antimony
  • Tartox
  • Tartrate antimonio-potassique
  • Tartrate antimonio-potassique [French]
  • Tartrated antimony
  • UNII-DL6OZ476V3

Systematic Names

  • Antimonate(2-), bis(mu-(2,3-di(hydroxy-kappaO)butanedioato(4-)-kappaO1:kappaO4))di-, dipotassium, trihydrate, stereoisomer
  • Antimonate(2-), bis(mu-(2,3-dihydroxybutanedioato(4-)-O(sup 1),O(sup 2):O(sup 3),O(sup 4)))-di-, dipotassium, trihydrate, stereoisomer
  • Antimonate(2-), bis(mu-(2,3-dihydroxybutanedioato(4-)-O1,O2:O3,O4))di-, dipotassium, trihydrate, stereoisomer
  • Antimonate(2-), bis(u-(2,3-dihydroxybutanedioato(4-)-O1,O2,O3,O4))di-, dipotassium, trihydrate
  • Antimony potassium tartrate

Superlist Names

  • Antimonate(2-), bis(mu-(2,3-dihydroxybutanedioato(4-)-O1,O2:O3,O4))di-, dipotassium, trihydrate, stereoisomer
  • Antimony potassium tartrate
  • Antimony potassium tartrate [UN1551] [Poison]
  • Potassium antimonyl tartrate
  • UN1551

Registry Numbers

CAS Registry Number

  • 28300-74-5

FDA UNII

  • DL6OZ476V3

Other Registry Numbers

  • 12125-10-9
  • 1332-41-8
  • 1332-43-0
  • 16039-64-8
  • 26282-95-1
  • 304-61-0
  • 53318-72-2
  • 8012-64-4

System Generated Number

  • 0028300745

Molecular Formulas

Molecular Formulas

  • C4-H4-K-O7-Sb
  • C4-H4-K2-O7-Sb
  • C8-H4-K2-O12-Sb2.3H2-O
  • C8-H4-O12-Sb2.3H2-O.2K

Molecular Formula Fragments

  • C8-H4-K2-O12-Sb2
  • C8-H4-O12-Sb2
  • COMPONENT
  • H2-O
  • K

Structure Descriptors

InChI

1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4/t2*1-,2-;;;;;;;/m11......./s1

InChIKey

WBTCZEPSIIFINA-MSFWTACDSA-J

Smiles

O.O.O.[K+].[K+].[Sb+3].[Sb+3].[O-][C@H]([C@@H]([O-])C(=O)[O-])C(=O)[O-].[O-][C@H]([C@@H]([O-])C(=O)[O-])C(=O)[O-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intraperitoneal 15mg/kg (15mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
guinea pig LDLo intramuscular 55mg/kg (55mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
human LDLo oral 2mg/kg (2mg/kg)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1097, 1966.
human TDLo intravenous 1392ug/kg (1.392mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Lancet. Vol. 210, Pg. 227, 1926.
man LD50 intravenous 249mg/kg/9D-I (249mg/kg)   Journal of Tropical Medicine and Hygiene. Vol. 21, Pg. 38, 1918.
man LD50 intravenous 249mg/kg/9D-I (249mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

GASTROINTESTINAL: NAUSEA OR VOMITING
Journal of Tropical Medicine and Hygiene. Vol. 21, Pg. 38, 1918.
man LDLo intravenous 12mg/kg/1W-I (12mg/kg) LIVER: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Lancet. Vol. 210, Pg. 227, 1926.
mouse LD50 intraperitoneal 33mg/kg (33mg/kg)   Bulletin of the World Health Organization. Vol. 53, Pg. 379, 1976.
mouse LD50 intravenous 45mg/kg (45mg/kg)   Fortschritte der Arzneimittelforschung. Progress in Drug Research. Vol. 17, Pg. 108, 1973.
mouse LD50 subcutaneous 55mg/kg (55mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Proceedings of the Society for Experimental Biology and Medicine. Vol. 129, Pg. 284, 1968.
mouse LDLo oral 600mg/kg (600mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rabbit LD50 intravenous 12mg/kg (12mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 196, 1947.
rabbit LD50 oral 115mg/kg (115mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat LD50 intraperitoneal 11mg/kg (11mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat LD50 oral 115mg/kg (115mg/kg)   Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 24, 1966.
rat LDLo intramuscular 33mg/kg (33mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.