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Substance Name: Choline alfoscerate [INN]
RN: 28319-77-9
UNII: 60M22SGW66


  • A component of PHOSPHATIDYLCHOLINES or LECITHINS, in which the two hydroxy groups of GLYCEROL are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules.

Molecular Formula

  • C8-H20-N-O6-P

Molecular Weight

  • 257.221

Classification Code

  • Drug / Therapeutic Agent
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Names and Synonyms

Name of Substance

  • Choline alfoscerate [INN]

MeSH Heading

  • Glycerylphosphorylcholine


  • Alfoscerate de choline
  • Alfoscerate de choline [INN-French]
  • Alfoscerato de colina
  • Alfoscerato de colina [INN-Spanish]
  • alpha-Glyceryl phosphoryl choline
  • BRN 6062450
  • Calcium (glycerophosphate de)
  • Calcium (glycerophosphate de) [DCF]
  • Choline alfoscerate
  • Choline alphoscerate
  • Cholini alfosceras
  • Cholini alfosceras [INN-Latin]
  • Cholini glycerophosphas
  • Cholini glycerophosphas [Latin]
  • Colina glicerofosfato
  • EINECS 248-962-2
  • Glicerofosfato de colina
  • Glicerofosfato de colina [Spanish]
  • Glycerophosphate de choline
  • Glycerophosphate de choline [French]
  • Glycerophosphocholine
  • Glycerophosphorylcholine
  • L-alpha-Glycerophosphocholine
  • L-alpha-Glycerophosphorylcholine
  • L-alpha-Glycerylphosphorylcholine
  • sn-Glycero-3-phosphocholine
  • UNII-60M22SGW66

Systematic Names

  • Choline glycerophosphate
  • Choline hydroxide, (R)-2,3-dihydroxypropyl hydrogen phosphate, inner salt
  • Choline, hydroxide, 2,3-dihydroxypropyl hydrogen phosphate, inner salt, D- (8CI)
  • Ethanaminium, 2-(((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt, (R)-

Registry Numbers

CAS Registry Number

  • 28319-77-9


  • 60M22SGW66

Other Registry Numbers

  • 103709-68-8
  • 117829-79-5

System Generated Number

  • 0028319779

Structure Descriptors








Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous > 650mg/kg (650mg/kg)   Japanese Kokai Tokyo Koho Patents. Vol. #93-32553,
mouse LD50 oral > 13gm/kg (13000mg/kg)   Japanese Kokai Tokyo Koho Patents. Vol. #93-32553,

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 142.5 deg C   EXP
log P (octanol-water) -5.150 (none)   EST
Atmospheric OH Rate Constant 7.63E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.