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Substance Name: Lerdelimumab [INN]
RN: 285985-06-0
UNII: GX1FEU3QSM

Note

  • Human anti-TGF beta 2 antibody for preventing post-operative scarring in patients undergoing surgery for glaucoma (trabulectomy); also has potential for the treatment of fibrosis, cataract, retinopathy and connective tissue disease.
 

Classification Codes

  • Monoclonal Antibody
  • Postoperative Anti-Scarring Agent in Glaucoma Surgery
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Names and Synonyms

Name of Substance

  • 6B1 IgG4 monoclonal antibody
  • Lerdelimumab [INN]

Synonyms

  • CAT-152
  • Human IgG-4 anti-TGFb2 monoclonal antibody
  • Immunoglobulin G4, anti-(human transforming growth factor beta2) (human monoclonal CAT-152 gamma4-chain), disulfide with human monoclonal CAT-152 lambda-chain, dimer
  • Lerdelimumab
  • UNII-GX1FEU3QSM

Systematic Name

  • Human IgG4 anti-transforming growth factor-beta 2 monoclonal antibody

Registry Numbers

CAS Registry Number

  • 285985-06-0

FDA UNII

  • GX1FEU3QSM

System Generated Number

  • 0285985060