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Substance Name: Dexamethasone mixture with tobramycin
RN: 288392-57-4
InChIKey: DWLNMMCXGSKYEM-VQHMUFKESA-N

Note

  • A topical preparation of tobramycin and dexamethasone that is used for treating or preventing superficial bacterial infections of the eye.

Molecular Formula

  • C22-H29-F-O5.C18-H37-N5-O9

Molecular Weight

  • 859.9804
 

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Hormones
  • Ophthalmic Solutions
  • Pharmaceutical Solutions
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Names and Synonyms

Name of Substance

  • Dexamethasone mixture with tobramycin

MeSH Heading

  • Tobramycin, dexamethasone drug combination

Synonyms

  • Dexamethasone-tobramycin mixt.
  • Tobradex
  • Tobradex ST
  • Tobramycin and dexamethasone

Systematic Name

  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-, mixt. with O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl-(1-4))-2-deoxy-D-streptamine

Registry Numbers

CAS Registry Number

  • 288392-57-4

System Generated Number

  • 0288392574

Molecular Formulas

Molecular Formula

  • C22-H29-F-O5.C18-H37-N5-O9

Molecular Formula Fragments

  • C18-H37-N5-O9
  • C22-H29-F-O5
  • COMPONENT

Structure Descriptors

InChI

1S/C22H29FO5.C18H37N5O9/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24;19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3;5-18,24-28H,1-4,19-23H2/t12-,15+,16+,17+,19+,20+,21+,22+;5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m10/s1

InChIKey

DWLNMMCXGSKYEM-VQHMUFKESA-N

Smiles

[C@@]12([C@H]([C@H]3[C@](C[C@@H]2O)([C@]([C@@H](C3)C)(C(=O)CO)O)C)CCC2=CC(=O)C=C[C@]12C)F.[C@H]1([C@H]([C@H](O[C@H]2O[C@@H]([C@H](C[C@H]2N)O)CN)[C@H](C[C@H]1N)N)O)O[C@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)N)O)CO