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Substance Name: Benzo(b)(1,8)naphthyridin-5(10H)-one, 7-chloro-10-(3-(dimethylamino)propyl)-, monohydrochloride
RN: 28907-45-1
InChIKey: DGUPZAJJVUHQHW-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H18-Cl-N3-O.Cl-H

Molecular Weight

  • 352.263
 
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Names and Synonyms

Synonyms

  • 7-Chloro-10-(3-dimethylaminopropyl)-benzo-(b)(1,8)-5(10H)-naphthayridone hydrochloride
  • C 45
  • C 45 (pharmaceutical)
  • Chlorowodorku 10-gamma-dwumetyloaminopropylo-7-chlorobenzo(b)-(1,8)-naftyrydonu-5
  • Chlorowodorku 10-gamma-dwumetyloaminopropylo-7-chlorobenzo(b)-(1,8)-naftyrydonu-5 [Polish]
  • IFC-45
  • IPF C-45

Systematic Name

  • Benzo(b)(1,8)naphthyridin-5(10H)-one, 7-chloro-10-(3-(dimethylamino)propyl)-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 28907-45-1

Related Registry Number

  • 28907-44-0 (Parent)

System Generated Number

  • 0028907451

Molecular Formulas

Molecular Formula

  • C17-H18-Cl-N3-O.Cl-H

Molecular Formula Fragments

  • C17-H18-Cl-N3-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C17H18ClN3O.ClH/c1-20(2)9-4-10-21-15-7-6-12(18)11-14(15)16(22)13-5-3-8-19-17(13)21;/h3,5-8,11H,4,9-10H2,1-2H3;1H

InChIKey

DGUPZAJJVUHQHW-UHFFFAOYSA-N

Smiles

c12n(c3c(cccn3)c(c1cc(Cl)cc2)=O)CCC[NH+](C)C.[ClH-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 106mg/kg (106mg/kg)   Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 503, 1975.
mouse LD50 intravenous 33mg/kg (33mg/kg)   Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 121, 1975.
mouse LD50 oral 200mg/kg (200mg/kg)   Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 121, 1975.
rabbit LD50 intravenous 12mg/kg (12mg/kg)   Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 503, 1975.
rat LD50 intraperitoneal 105mg/kg (105mg/kg)   Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 503, 1975.
rat LD50 intravenous 33mg/kg (33mg/kg)   Polish Journal of Pharmacology and Pharmacy. Vol. 29, Pg. 23, 1977.
rat LD50 oral 500mg/kg (500mg/kg)   Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 503, 1975.
rat LD50 subcutaneous 136mg/kg (136mg/kg)   Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 34, Pg. 115, 1977.