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Substance Name: Dextromoramide tartrate
RN: 2922-44-3
UNII: J778U505W5
InChIKey: ACRMUSVWIFZVSM-JTHHODAVSA-N

Note

  • An opioid analgesic structurally related to METHADONE and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)

Molecular Formula

  • C25-H32-N2-O2.C4-H6-O6

Molecular Weight

  • 542.625
 

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect
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Names and Synonyms

Name of Substance

  • Dextromoramide tartrate

Synonyms

  • (+)-1-(3-Methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidine tartrate
  • (+)-4-(2-Methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine bitartrate
  • d-3-Methyl-2,2-diphenyl-4-morpholinobutyrylpyrrolidine tartrate
  • D-Moramide tartrate
  • Dextromoramide bitartrate
  • Dextromoramide tartrate
  • Dimorlin tartrate
  • EINECS 220-870-7
  • Jetrium tartrate
  • Palphium tartrate
  • Pyrrolamidol tartrate
  • R-875 tartrate
  • SKF 5137 tartrate
  • UNII-J778U505W5

Systematic Names

  • (+)-4-(2-Methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine bitartrate
  • Dextromoramide hydrogen (+)-tartrate
  • Pyrrolidine, 1-(3-methyl-4-morpholino-2,2-diphenylbutyryl)-, (+)-, tartrate (1:1)

Registry Numbers

CAS Registry Number

  • 2922-44-3

FDA UNII

  • J778U505W5

Other Registry Number

  • 3528-84-5

System Generated Number

  • 0002922443

Molecular Formulas

Molecular Formula

  • C25-H32-N2-O2.C4-H6-O6

Molecular Formula Fragments

  • C25-H32-N2-O2
  • C4-H6-O6
  • COMPONENT

Structure Descriptors

InChI

1S/C25H32N2O2.C4H6O6/c1-21(20-26-16-18-29-19-17-26)25(22-10-4-2-5-11-22,23-12-6-3-7-13-23)24(28)27-14-8-9-15-27;5-1(3(7)8)2(6)4(9)10/h2-7,10-13,21H,8-9,14-20H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t21-;1-,2-/m11/s1

InChIKey

ACRMUSVWIFZVSM-JTHHODAVSA-N

Smiles

C([C@H](O)[C@@H](O)C(=O)O)(=O)O.c1(ccccc1)C([C@@H](CN1CCOCC1)C)(C(N1CCCC1)=O)c1ccccc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 subcutaneous 150mg/kg (150mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 135, Pg. 462, 1962.
rat LD50 oral 71800ug/kg (71.8mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 862, 1971.
rat LD50 subcutaneous 54mg/kg (54mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 862, 1971.