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Substance Name: Pseudolycorine
RN: 29429-03-6
InChIKey: CKAHWDNDUGDSLE-ARLBYUKCSA-N

Note

  • Alkaloid isolated from Narcissus tazetta var. chinensis Roem, N. papyraceus or Lycoris radiata Herb.

Classification Codes

  • Drug / Therapeutic Agent
  • Natural Product

Molecular Formula

  • C16-H19-N-O4

Molecular Weight

  • 289.3291
 
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Names and Synonyms

Name of Substance

  • Pseudolycorine

Synonyms

  • Pseudolycorine
  • psi-Lycorine

Systematic Names

  • 10,11-Secolycoran-1-alpha,2-beta-diol, 3,3a-didehydro-
  • Galanthan-1,2,10-triol, 3,12-didehydro-9-methoxy-, (1-alpha,2-beta)- (9CI)

Registry Numbers

CAS Registry Number

  • 29429-03-6

System Generated Number

  • 0029429036

Structure Descriptors

InChI

1S/C16H19NO4/c1-21-13-5-9-7-17-3-2-8-4-12(19)16(20)14(15(8)17)10(9)6-11(13)18/h4-6,12,14-16,18-20H,2-3,7H2,1H3/t12-,14-,15+,16+/m0/s1

InChIKey

CKAHWDNDUGDSLE-ARLBYUKCSA-N

Smiles

COc1cc2c(cc1O)[C@@H]3[C@@H]([C@H](C=C4[C@H]3N(C2)CC4)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 881mg/kg (881mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. Vol. 14, Pg. 705, 1979.
rat LD50 intraperitoneal 110mg/kg (110mg/kg)   Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. Vol. 14, Pg. 705, 1979.