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Substance Name: Mepazine chloride
RN: 2975-36-2
UNII: TIW15Q5R21
InChIKey: RLCFKYRNUBRPIK-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C19-H22-N2-S.Cl-H

Molecular Weight

  • 346.924
 
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Names and Synonyms

Results Name

  • Mepazine chloride

Name of Substance

  • Mepazine hydrochloride

Synonyms

  • 1-Pipecoline, 3-(phenothiazin-10-yl)methyl-, hydrochloride
  • 10-((1-Methyl-3-piperidyl)methyl)phenothiazine hydrochloride
  • EINECS 221-020-8
  • Mepazine chloride
  • Mepazine hydrochloride
  • NSC 64076
  • Pecazine hydrochloride
  • Pecazine monohydrochloride
  • Phenothiazine, 10-((1-methyl-3-piperidyl)methyl)-, hydrochloride
  • UNII-TIW15Q5R21

Systematic Names

  • 10-((1-Methyl-3-piperidyl)methyl)-10H-phenothiazine monohydrochloride
  • 10H-Phenothiazine, 10-((1-methyl-3-piperidinyl)methyl)-, monohydrochloride (9CI)
  • Phenothiazine, 10-((1-methyl-3-piperidyl)methyl)-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 2975-36-2

FDA UNII

  • TIW15Q5R21

Related Registry Number

  • 60-89-9 (Parent)

System Generated Number

  • 0002975362

Molecular Formulas

Molecular Formula

  • C19-H22-N2-S.Cl-H

Molecular Formula Fragments

  • C19-H22-N2-S
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C19H22N2S.ClH/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21;/h2-5,8-11,15H,6-7,12-14H2,1H3;1H

InChIKey

RLCFKYRNUBRPIK-UHFFFAOYSA-N

Smiles

N1(c2c(cccc2)Sc2c1cccc2)C[C@@H]1C[N@@](C)CCC1.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 200mg/kg (200mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 28, 1972.
mouse LD50 intravenous 62mg/kg (62mg/kg) BEHAVIORAL: SLEEP Acta Pharmacologica et Toxicologica. Vol. 19, Pg. 87, 1962.
mouse LD50 oral 155mg/kg (155mg/kg)   Cesko-Slovenska Farmacie. Vol. 6, Pg. 365, 1957.
mouse LD50 subcutaneous 750mg/kg (750mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 28, 1972.
rabbit LD50 intravenous 20mg/kg (20mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 28, 1972.
rabbit LD50 oral 1gm/kg (1000mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 28, 1972.
rat LD50 intravenous 20mg/kg (20mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 28, 1972.
rat LD50 oral 1gm/kg (1000mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 28, 1972.