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Substance Name: Indriline hydrochloride [USAN]
RN: 2988-32-1
UNII: W6JCQ2O9YK
InChIKey: ZTCKJGNZNKVHOJ-UHFFFAOYSA-N

Classification Code

  • Stimulant (Central)

Molecular Formula

  • C19-H21-N.Cl-H

Molecular Weight

  • 299.843
 
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Names and Synonyms

Name of Substance

  • Indriline hydrochloride [USAN]

Synonyms

  • 1-(2-Dimethylaminoethyl)-1-phenylindene hydrochloride
  • Chlorhydrate de 1-(2-dimethylaminoethyl)-1-phenylindene
  • Chlorhydrate de 1-(2-dimethylaminoethyl)-1-phenylindene [French]
  • Indriline HCl
  • Indriline hydrochloride
  • Indrilline hydrochloride
  • MJ 1986
  • MJ 2327 HCl
  • N,N-Dimethyl-1-phenylindene-1-ethylamine hydrochloride
  • NSC 169093
  • UNII-W6JCQ2O9YK

Systematic Names

  • 1H-Indene-1-ethanamine, N,N-dimethyl-1-phenyl-, hydrochloride
  • Indene-1-ethylamine, N,N-dimethyl-1-phenyl-, hydrochloride

Registry Numbers

CAS Registry Number

  • 2988-32-1

FDA UNII

  • W6JCQ2O9YK

System Generated Number

  • 0002988321

Molecular Formulas

Molecular Formula

  • C19-H21-N.Cl-H

Molecular Formula Fragments

  • C19-H21-N
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C19H21N.ClH/c1-20(2)15-14-19(17-9-4-3-5-10-17)13-12-16-8-6-7-11-18(16)19;/h3-13H,14-15H2,1-2H3;1H

InChIKey

ZTCKJGNZNKVHOJ-UHFFFAOYSA-N

Smiles

c1ccc2c(c1)C=C[C@@]2(c1ccccc1)CCN(C)C.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 95mg/kg (95mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Therapie. Vol. 23, Pg. 1135, 1968.
mouse LD50 intraperitoneal 53mg/kg (53mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 370, 1972.
mouse LD50 intravenous 31mg/kg (31mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Therapie. Vol. 23, Pg. 1135, 1968.
mouse LD50 oral 84mg/kg (84mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 370, 1972.
mouse LD50 unreported 41mg/kg (41mg/kg) AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)" Journal of Medicinal Chemistry. Vol. 10, Pg. 418, 1967.
rat LD50 intraperitoneal 95mg/kg (95mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Therapie. Vol. 23, Pg. 1135, 1968.
rat LD50 intravenous 27mg/kg (27mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Therapie. Vol. 23, Pg. 1135, 1968.
rat LD50 oral 385mg/kg (385mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 370, 1972.