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Substance Name: Vidarabine phosphate [USAN]
RN: 29984-33-6
UNII: 106XV160TZ
InChIKey: UDMBCSSLTHHNCD-UHTZMRCNSA-N

Note

  • An adenosine monophosphate analog in which ribose is replaced by an arabinose moiety. It is the monophosphate ester of VIDARABINE with antiviral and possibly antineoplastic properties.

Molecular Formula

  • C10-H14-N5-O7-P

Molecular Weight

  • 347.2226
 

Classification Codes

  • Anti-Infective Agents
  • Antimetabolites
  • Antiviral
  • Antiviral Agents
  • Drug / Therapeutic Agent
  • Noxae
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Names and Synonyms

Name of Substance

  • Vidarabine phosphate
  • Vidarabine phosphate [USAN]

MeSH Heading

  • Vidarabine phosphate

Synonyms

  • 5'-Arabinosyladenine monophosphate
  • 9-(5-O-Phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine
  • 9-beta-D-Arabinofuranosyladenine 5'-(dihydrogen phosphate)
  • 9-beta-D-Arabinofuranosyladenine 5'-monophosphate
  • 9-beta-D-Arabinofuranosyladenine 5'-phosphate
  • 9-beta-D-Arabinofuranosyladenine monophosphate
  • 9H-Purin-6-amine, 9-(5-O-phosphono-beta-D-arabinofuranosyl)-
  • Adenine arabinonucleoside 5'-phosphate
  • Adenine arabinoside 5'-monophosphate
  • Adenine arabinoside monophosphate
  • Adenine, 9beta-D-arabinofuranosyl-, 5'-(dihydrogen phosphate)
  • Ara-AMP
  • Arabinosyladenine monophosphate
  • CI-808
  • CL-808
  • D-Arabinosyladenine 5'-monophosphate
  • EINECS 249-990-8
  • NSC 127223
  • UNII-106XV160TZ
  • Vidarabine 5'-monophosphate
  • Vidarabine monophosphate
  • Vidarabine phosphate
  • Vidarabine-5'-monophosphate

Systematic Names

  • 9-(5-O-Phosphono-beta-D-arabinofuranosyl)adenine
  • 9H-Purin-6-amine, 9-(5-O-phosphono-beta-D-arabinofuranosyl)-
  • Adenine, 9-beta-D-arabinofuranosyl-, 5'-(dihydrogen phosphate)

Registry Numbers

CAS Registry Number

  • 29984-33-6

FDA UNII

  • 106XV160TZ

System Generated Number

  • 0029984336

Structure Descriptors

InChI

1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7+,10-/m1/s1

InChIKey

UDMBCSSLTHHNCD-UHTZMRCNSA-N

Smiles

Nc1ncnc2c1ncn2[C@@H]3O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]3O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 intraperitoneal 1700mg/kg (1700mg/kg) LIVER: OTHER CHANGES Annals of the New York Academy of Sciences. Vol. 284, Pg. 6, 1977.
rat LD50 intravenous 1200mg/kg (1200mg/kg) LIVER: OTHER CHANGES Annals of the New York Academy of Sciences. Vol. 284, Pg. 6, 1977.