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Substance Name: Cyclobenzaprine [INN]
RN: 303-53-7
UNII: 69O5WQQ5TI
InChIKey: JURKNVYFZMSNLP-UHFFFAOYSA-N
Note
- Lisseril is synonymous for HCl.
Molecular Formula
- C20-H21-N
Molecular Weight
- 275.3929
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Antidepressive Agents
- Antidepressive Agents, Tricyclic
- Central Nervous System Agents
- Central Nervous System Depressants
- Drug / Therapeutic Agent
- Muscle Relaxants, Central
- Mutation Data
- Neuromuscular Agents
- Peripheral Nervous System Agents
- Psychotropic Drugs
- Tranquilizing Agents
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Links to Resources
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Names and Synonyms
Name of Substance
- Cyclobenzaprine
- Cyclobenzaprine [INN]
Synonyms
- 10,11-Dehydroamitriptyline
- 5-(3-Dimetilaminopropiliden)-5H-dibenzo-(a,d)-ciclopentene
- 5-(3-Dimetilaminopropiliden)-5H-dibenzo-(a,d)-ciclopentene [Italian]
- 9715 R.P.
- Ciclobenzaprina
- Ciclobenzaprina [INN-Spanish]
- Cyclobenzaprine
- Cyclobenzaprinum
- Cyclobenzaprinum [INN-Latin]
- EINECS 206-145-8
- Fexmid
- HSDB 8305
- Lisseril
- MK 130
- N,N-Dimethyl-5H-dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine
- Proeptatriene
- Proeptatriene [Italian]
- Proheptatrien
- Proheptatriene
- Ro 4-1577
- UNII-69O5WQQ5TI
Systematic Names
- 1-Propanamine, 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-
- 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, N,N-dimethyl-
- Cyclobenzaprine
- N,N-Dimethyl-3-(dibenzo(a,d)cycloheptene-4-ylidene)propylamine
Registry Numbers
CAS Registry Number
- 303-53-7
FDA UNII
- 69O5WQQ5TI
Related Registry Number
- 6202-23-9 (hydrochloride)
System Generated Number
- 0000303537
Structure Descriptors
InChI
InChI=1S/C20H21N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-14H,7,15H2,1-2H3InChIKey
JURKNVYFZMSNLP-UHFFFAOYSA-NSmiles
CN(C)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 90mg/kg (90mg/kg) | Journal of Medicinal Chemistry. Vol. 6, Pg. 338, 1963. | |
| mouse | LD50 | intravenous | 36mg/kg (36mg/kg) | Farmaco, Edizione Pratica. Vol. 25, Pg. 519, 1970. | |
| mouse | LD50 | oral | 250mg/kg (250mg/kg) | Farmaco, Edizione Pratica. Vol. 25, Pg. 519, 1970. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| log P (octanol-water) | 4.790 | (none) | EST | |
| Atmospheric OH Rate Constant | 1.95E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.