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Substance Name: Depramine [INN:BAN]
RN: 303-54-8
UNII: 77C3T28736
InChIKey: AFBYHZACPPSJKD-UHFFFAOYSA-N

Molecular Formula

  • C19-H22-N2

Molecular Weight

  • 278.3968
 
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Names and Synonyms

Name of Substance

  • Depramine
  • Depramine [INN:BAN]

Synonyms

  • 10,11-Dehydroimipramine
  • 5-(3-(Dimethylamino)propyl)-5H-dibenz(b,f)azepine
  • 5-20-08-00247 (Beilstein Handbook Reference)
  • Balipramine
  • BRN 1319717
  • Depramina
  • Depramina [INN-Spanish]
  • Depramine
  • Depraminum
  • Depraminum [INN-Latin]
  • GP 31406
  • UNII-77C3T28736

Systematic Names

  • 5-(3-(Dimethylamino)propyl)-5H-dibenz(b,f)azepine
  • 5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-
  • 5H-Dibenz(b,f)azepine-5-propanamine, N,N-dimethyl- (9CI)

Registry Numbers

CAS Registry Number

  • 303-54-8

FDA UNII

  • 77C3T28736

Related Registry Numbers

  • 58262-51-4 (hydrochloride)
  • 72629-48-2 (fumarate[1:1])

System Generated Number

  • 0000303548

Structure Descriptors

InChI

1S/C19H22N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-13H,7,14-15H2,1-2H3

InChIKey

AFBYHZACPPSJKD-UHFFFAOYSA-N

Smiles

N1(c2c(C=Cc3c1cccc3)cccc2)CCCN(C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 41mg/kg (41mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 120, Pg. 450, 1959.
rabbit LD50 intravenous 6mg/kg (6mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 120, Pg. 450, 1959.
rat LD50 intravenous 23mg/kg (23mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 120, Pg. 450, 1959.