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Substance Name: 2-Hydroxyimipramine
RN: 303-70-8
UNII: S0L1IZR63V
InChIKey: ROTCPJFWLNDKHU-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C19-H24-N2-O

Molecular Weight

  • 296.4116
 
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Names and Synonyms

Name of Substance

  • 2-Hydroxyimipramine

Synonyms

  • 2-Hydroxyimipramine
  • 2-OH-IP
  • 5-(3-(Dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepin-2-ol
  • 5-(3-(Dimethylamino)propyl)-2-hydroxy-10,11-dihydro-5H-dibenz(b,f)azepine
  • 5-21-04-00033 (Beilstein Handbook Reference)
  • BRN 1547775
  • G 33679
  • GP 33679
  • Hydroxyimipramine
  • UNII-S0L1IZR63V

Systematic Name

  • 5H-Dibenz(b,f)azepin-2-ol, 10,11-dihydro-5-(3-(dimethylamino)propyl)-

Registry Numbers

CAS Registry Number

  • 303-70-8

FDA UNII

  • S0L1IZR63V

System Generated Number

  • 0000303708

Structure Descriptors

InChI

1S/C19H24N2O/c1-20(2)12-5-13-21-18-7-4-3-6-15(18)8-9-16-14-17(22)10-11-19(16)21/h3-4,6-7,10-11,14,22H,5,8-9,12-13H2,1-2H3

InChIKey

ROTCPJFWLNDKHU-UHFFFAOYSA-N

Smiles

c12cc(O)ccc1N(c1ccccc1CC2)CCCN(C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 29mg/kg (29mg/kg)   Medicina et Pharmacologia Experimentalis. Vol. 15, Pg. 187, 1966.
mouse LD50 oral 733mg/kg (733mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1617, 1969.
rabbit LD50 intravenous 12500ug/kg (12.5mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1617, 1969.
rat LD50 intravenous 19mg/kg (19mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1617, 1969.
rat LD50 oral 2980mg/kg (2980mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1617, 1969.