Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Etofenamate [USAN:INN:BAN]
RN: 30544-47-9
UNII: KZF0XM66JC
InChIKey: XILVEPYQJIOVNB-UHFFFAOYSA-N

Molecular Formula

  • C18-H18-F3-N-O4

Molecular Weight

  • 369.337
 

Classification Codes

  • Analgesic
  • Analgesics
  • Analgesics, Non-Narcotic
  • Anti-Inflammatory
  • Anti-Inflammatory Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antirheumatic Agents
  • Drug / Therapeutic Agent
  • Peripheral Nervous System Agents
  • Reproductive Effect
  • Sensory System Agents
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Etofenamate
  • Etofenamate [USAN:INN:BAN]

Synonyms

  • 2-(2-Hydroxyaethoxy)aethylester der flutenaminsaeure
  • 2-(2-Hydroxyaethoxy)aethylester der flutenaminsaeure [German]
  • 2-(2-Hydroxyethoxy)ethyl N-(alpha,alpha,alpha-trifluoro-m-tolyl)anthranilate
  • 2-(2-Hydroxyethoxy)ethyl-N-(alpha,alpha,alpha-trifluoro-m-tolyl)anthranilate
  • Bay d 1107
  • Bayrogel
  • Benzoic acid, 2-((3-(trifluoromethyl)phenyl)amino)-, 2-(2-hydroxyethoxy)ethyl ester
  • BRN 2953263
  • EINECS 250-231-8
  • Etofenamate
  • Etofenamato
  • Etofenamato [INN-Spanish]
  • Etofenamatum
  • Etofenamatum [INN-Latin]
  • Rheumon
  • Rheumon gel
  • TVX 485
  • TVX485
  • UNII-KZF0XM66JC
  • WHR 5020
  • WHR-5020

Systematic Names

  • Anthranilic acid, N-(alpha,alpha,alpha-trifluoro-m-tolyl)-, 2-(2-hydroxyethoxy)ethyl ester
  • Benzoic acid, 2-((3-(trifluoromethyl)phenyl)amino)-, 2-(2-hydroxyethoxy)ethyl ester
  • Etofenamate

Registry Numbers

CAS Registry Number

  • 30544-47-9

FDA UNII

  • KZF0XM66JC

System Generated Number

  • 0030544479

Structure Descriptors

InChI

1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2

InChIKey

XILVEPYQJIOVNB-UHFFFAOYSA-N

Smiles

c1(c(cccc1)C(OCCOCCO)=O)Nc1cc(ccc1)C(F)(F)F

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 75mg/kg (75mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 5225, 1982.
mouse LD50 oral 743mg/kg (743mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1333, 1977.
mouse LD50 subcutaneous 1897mg/kg (1897mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BLOOD: NORMOCYTIC ANEMIA

GASTROINTESTINAL: OTHER CHANGES
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 5225, 1982.
rabbit LD50 subcutaneous 1532mg/kg (1532mg/kg) BLOOD: NORMOCYTIC ANEMIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: OTHER CHANGES
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 5225, 1982.
rat LD50 intraperitoneal 373mg/kg (373mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1333, 1977.
rat LD50 intravenous 139mg/kg (139mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 5225, 1982.
rat LD50 oral 292mg/kg (292mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1333, 1977.
rat LD50 subcutaneous 568mg/kg (568mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1333, 1977.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point < 25 deg C   EXP
log P (octanol-water) 4.200 (none)   EST
Water Solubility 1.6 mg/L 22 EXP
Atmospheric OH Rate Constant 8.96E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.