Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Pargyline hydrochloride [USAN:USP]
RN: 306-07-0
UNII: W70V6I2OMY
InChIKey: BCXCABRDBBWWGY-UHFFFAOYSA-N

Note

  • A monoamine oxidase inhibitor with antihypertensive properties.

Molecular Formula

  • C11-H13-N.Cl-H

Molecular Weight

  • 195.692
 

Classification Codes

  • Antihypertensive
  • Drug / Therapeutic Agent
  • Human Data
  • Reproductive Effect
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Pargyline hydrochloride
  • Pargyline hydrochloride [USAN:USP]

Synonyms

  • 2-Propynylamine, N-benzyl-N-methyl-, hydrochloride
  • A-19120
  • AI3-62178
  • Benzylmethylpropynylamine hydrochloride
  • EINECS 206-175-1
  • Eutonyl
  • Eutonyl-ten
  • Methylbenzylpropynylamine hydrochloride
  • MO-911
  • N-Benzyl-N-methyl-2-propynylamine hydrochloride
  • N-Methyl-N-2-propynylbenzylamine hydrochloride
  • NSC 43798
  • Pargyline chloride
  • Pargyline HCl
  • Pargyline hydrochloride
  • UNII-W70V6I2OMY
  • USAF A-19120

Systematic Names

  • Benzenemethanamine, N-methyl-N-2-propynyl-, hydrochloride
  • Benzylamine, N-methyl-N-2-propynyl-, hydrochloride
  • Pargyline hydrochloride

Mixture Name

  • Eutron

Registry Numbers

CAS Registry Number

  • 306-07-0

FDA UNII

  • W70V6I2OMY

Other Registry Number

  • 8055-70-7

System Generated Number

  • 0000306070

Molecular Formulas

Molecular Formula

  • C11-H13-N.Cl-H

Molecular Formula Fragments

  • C11-H13-N
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H

InChIKey

BCXCABRDBBWWGY-UHFFFAOYSA-N

Smiles

c1(C[N@@](CC#C)C)ccccc1.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 intraperitoneal 200mg/kg (200mg/kg)   Annals of the New York Academy of Sciences. Vol. 107, Pg. 1068, 1963.
dog LD50 oral 175mg/kg (175mg/kg)   Annals of the New York Academy of Sciences. Vol. 107, Pg. 1068, 1963.
man TDLo oral 108mg/kg/26W- (108mg/kg) BEHAVIORAL: EUPHORIA Journal of Clinical Psychiatry. Vol. 44, Pg. 25, 1983.
monkey LD50 intraperitoneal > 100mg/kg (100mg/kg)   Annals of the New York Academy of Sciences. Vol. 107, Pg. 1068, 1963.
monkey LD50 oral > 100mg/kg (100mg/kg)   Annals of the New York Academy of Sciences. Vol. 107, Pg. 1068, 1963.
mouse LD50 intraperitoneal 300mg/kg (300mg/kg)   National Technical Information Service. Vol. AD277-689,
mouse LD50 intravenous 99mg/kg (99mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Pharmaceutical Sciences. Vol. 57, Pg. 430, 1968.
mouse LD50 oral 680mg/kg (680mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Annals of the New York Academy of Sciences. Vol. 107, Pg. 1068, 1963.
rat LD50 intraperitoneal 142mg/kg (142mg/kg)   Annals of the New York Academy of Sciences. Vol. 107, Pg. 1068, 1963.
rat LD50 intravenous 175mg/kg (175mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 401, 1972.
rat LD50 oral 250mg/kg (250mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 401, 1972.
women TDLo oral 1500ug/kg/D (1.5mg/kg) BEHAVIORAL: FLUID INTAKE American Journal of Psychiatry. Vol. 118, Pg. 255, 1961.