Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Tumor Necrosis Factor-alpha
RN: 308079-78-9
UNII: 4TVX2I407K

Note

  • Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta ( LYMPHOTOXIN), but they share TNF RECEPTORS.
 

Names and Synonyms

Name of Substance

  • Tumor Necrosis Factor-alpha

MeSH Heading

  • Tumor Necrosis Factor-alpha

Synonyms

  • Cachectin
  • Cachectin proteins
  • Cachectins
  • Lymphokines and Cytokines, tumor necrosis factor
  • TNF
  • TNF alpha
  • TNF Receptor Ligands
  • TNF-alpha
  • TNFalpha
  • Tumor necrosis factor
  • Tumor necrosis factor alpha
  • Tumor Necrosis Factors
  • UNII-4TVX2I407K

Registry Numbers

CAS Registry Number

  • 308079-78-9

FDA UNII

  • 4TVX2I407K

System Generated Number

  • 0308079789

Structure Descriptors

Smiles

[*]