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Substance Name: Apomorphine hydrochloride
RN: 314-19-2


  • A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use.

Molecular Formula

  • C17-H17-N-O2.Cl-H

Molecular Weight

  • 303.787

Classification Code

  • Mutation Data
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Names and Synonyms

Results Name

  • Apomorphine hydrochloride

Name of Substance

  • Apomorphine hydrochloride
  • Apomorphine hydrochloride anhydrous


  • (-)-Apomorphinium hydrochloride
  • (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol hydrochlorid
  • 5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol hydrochlorid
  • 6a-beta-Aporphine-10,11-diol, hydrochloride
  • 6a-beta-Noraporphine-10,11-diol, 6-methyl-, hydrochloride
  • 6abeta-Noraporphine-10,11-diol, 6-methyl-, hydrochloride
  • Apokyn
  • Apomorphin hydrochlorid
  • Apomorphine
  • Apomorphine chloride
  • Apomorphine HCl
  • Apomorphine hydrochloride
  • Apomorphine SL
  • Apomorphinium chloride
  • Apomorphinum hydrochloricum
  • EINECS 206-243-0
  • N-Methylnorapomorphine hydrochloride
  • NSC 11442
  • pomorphini hydrochloridum
  • UNII-9K13MD7A0D
  • Uprima

Systematic Names

  • 4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)-
  • 4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, (6aR)-
  • 6abeta-Aporphine-10,11-diol, hydrochloride (8CI)
  • Apomorphine hydrochloride

Registry Numbers

CAS Registry Number

  • 314-19-2


  • 9K13MD7A0D

Other Registry Number

  • 5896-07-1

Related Registry Number

  • 58-00-4 (Parent)

System Generated Number

  • 0000314192

Molecular Formulas

Molecular Formula

  • C17-H17-N-O2.Cl-H

Molecular Formula Fragments

  • C17-H17-N-O2
  • Cl-H

Structure Descriptors








Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo intraarterial 30mg/kg (30mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig LDLo intravenous 20mg/kg (20mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
mouse LD50 intraperitoneal 145ug/kg (0.145mg/kg)   Journal of Medicinal Chemistry. Vol. 18, Pg. 1194, 1975.
mouse LD50 intravenous 38mg/kg (38mg/kg)   Toxicology and Applied Pharmacology. Vol. 6, Pg. 334, 1964.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 0.240 (none)   EST
Water Solubility 2.00E+04 mg/L 25 EXP
Vapor Pressure 2.36E-15 mm Hg 25 EST
Henry's Law Constant 3.66E-23 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 9.54E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.