Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Flubendazole [USAN:INN:BAN]
RN: 31430-15-6
UNII: R8M46911LR
InChIKey: CPEUVMUXAHMANV-UHFFFAOYSA-N

Note

  • The p-fluoro analog of mebendazole.

Molecular Formula

  • C16-H12-F-N3-O3

Molecular Weight

  • 313.2868
 

Classification Codes

  • Anthelmintics
  • Anti-Infective Agents
  • Antinematodal Agents
  • Antiparasitic Agents
  • Antiprotozoal
  • Drug / Therapeutic Agent
  • Mutation Data
  • Reproductive Effect
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Flubendazole
  • Flubendazole [USAN:INN:BAN]

Synonyms

  • (5-(4-Fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester
  • Carbamic acid, (5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl)-, methyl ester
  • CCRIS 4480
  • EINECS 250-624-4
  • Flubendazol
  • Flubendazol [INN-Spanish]
  • Flubendazole
  • Flubendazolum
  • Flubendazolum [INN-Latin]
  • Flubenol
  • Flumoxal
  • Flumoxane
  • Fluvermal
  • Methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate
  • Methyl N-(5-(p-fluorobenzoyl)-2-benzimidazolyl)carbamate
  • NSC 313680
  • R 17,889
  • R 17899
  • UNII-R8M46911LR

Systematic Names

  • 2-Benzimidazolecarbamic acid, 5-(p-fluorobenzoyl)-, methyl ester
  • Carbamic acid, (5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl)-, methyl ester
  • Flubendazole

Registry Numbers

CAS Registry Number

  • 31430-15-6

FDA UNII

  • R8M46911LR

System Generated Number

  • 0031430156

Structure Descriptors

InChI

1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22)

InChIKey

CPEUVMUXAHMANV-UHFFFAOYSA-N

Smiles

c12c([nH]c(n2)NC(=O)OC)ccc(c1)C(=O)c1ccc(cc1)F

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral > 2560mg/kg (2560mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 605, 1978.
mouse LD50 oral > 2560mg/kg (2560mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 605, 1978.
rabbit LD50 oral 2560mg/kg (2560mg/kg)   Yonsei Reports on Tropical Medicine. Vol. 9, Pg. 11, 1978.
rat LD50 oral 2560mg/kg (2560mg/kg)   Yonsei Reports on Tropical Medicine. Vol. 9, Pg. 11, 1978.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 260 deg C   EXP
log P (octanol-water) 2.910 (none)   EST
Atmospheric OH Rate Constant 1.36E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.