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Substance Name: Bucricaine [INN]
RN: 316-15-4
UNII: HUC352BGYM
InChIKey: ZFPNOTAGQWNERF-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H22-N2

Molecular Weight

  • 254.375
 
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Names and Synonyms

Name of Substance

  • Bucricaine [INN]

Synonyms

  • 1,2,3,4-Tetrahydro-N-butyl-9-acridinamine
  • 4-Butylamino-2,3-tetramethylenequinoline
  • 5-22-10-00480 (Beilstein Handbook Reference)
  • 9-Acridinamine, 1,2,3,4-tetrahydro-N-butyl-
  • 9-Butylamino-1,2,3,4-tetrahydroacridine
  • Acridine, 9-butylamino-1,2,3,4-tetrahydro-
  • BRN 0481616
  • Bucricaina
  • Bucricaina [Spanish]
  • Bucricaine
  • Bucricainum
  • Bucricainum [Latin]
  • Centbucridin
  • UNII-HUC352BGYM

Systematic Names

  • 9-(Butylamino)-1,2,3,4-tetrahydroacridine
  • Acridine, 1,2,3,4-tetrahydro-9-butylamino-

Registry Numbers

CAS Registry Number

  • 316-15-4

FDA UNII

  • HUC352BGYM

System Generated Number

  • 0000316154

Structure Descriptors

InChI

1S/C17H22N2/c1-2-3-12-18-17-13-8-4-6-10-15(13)19-16-11-7-5-9-14(16)17/h4,6,8,10H,2-3,5,7,9,11-12H2,1H3,(H,18,19)

InChIKey

ZFPNOTAGQWNERF-UHFFFAOYSA-N

Smiles

c1(c2c(nc3c1CCCC3)cccc2)NCCCC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 intraperitoneal 20mg/kg (20mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANALGESIA
Pharmaceutical Chemistry Journal Vol. 5, Pg. 654, 1971.
mouse LD50 intraperitoneal 50mg/kg (50mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Journal of Medicinal Chemistry. Vol. 9, Pg. 483, 1966.