Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Axitinib [USAN:INN:JAN]
RN: 319460-85-0
UNII: C9LVQ0YUXG
InChIKey: RITAVMQDGBJQJZ-FMIVXFBMSA-N

Note

  • Oral Angiogenesis Inhibitor that inhibits the tyrosine kinase activities of both VEGFR and PDGFRbeta.

Molecular Formula

  • C22-H18-N4-O-S

Molecular Weight

  • 386.4772
 

Classification Codes

  • Antineoplastic Agents
  • Antineoplastic, Inhibitor of VEGF/PDGF Tyrosine Kinases
  • Enzyme Inhibitors
  • Protein Kinase Inhibitors

Names and Synonyms

Name of Substance

  • Axitinib
  • Axitinib [USAN:INN:JAN]

Synonyms

  • AG 013736
  • AG-013736
  • Axitinib
  • Inlyta
  • N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide
  • UNII-C9LVQ0YUXG

Systematic Name

  • Benzamide, N-methyl-2-((3-((1E)-2-(2-pyridinyl)ethenyl)-1H-indazo)-6-yl)thio)-

Registry Numbers

CAS Registry Number

  • 319460-85-0

FDA UNII

  • C9LVQ0YUXG

Other Registry Number

  • 790713-39-2

System Generated Number

  • 0319460850

Structure Descriptors

InChI

1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+

InChIKey

RITAVMQDGBJQJZ-FMIVXFBMSA-N

Smiles

CNC(=O)c1ccccc1Sc2ccc3c(c2)[nH]nc3/C=C/c4ccccn4