Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Angiotensin II [USAN]
RN: 32044-01-2
UNII: 31L3HS630A
InChIKey: VBTZKFAHKJXHBA-PIONDTTLSA-N

Note

  • An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.

Molecular Formula

  • C50-H71-N13-O12.C2-H4-O2

Molecular Weight

  • 1106.2415
 

Classification Codes

  • Cardiovascular Agents
  • Treatment of Catecholamine-Resistant Hypotension (CRH)
  • Vasoconstrictor Agents
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Angiotensin II acetate
  • Angiotensin II [USAN]

Synonyms

  • Alanine, N-(1-(N-(N-(N-(N-(N2-L-alpha-aspartyl-L-arginyl)-L-valyl)-L-tyrosyl)-L-isoleucyl)-L-histidyl)-L-prolyl)-3-phenyl-, monoacetate salt, L-
  • Angiotensin II
  • Angiotensin II acetate
  • Angiotensin II acetate human
  • Angiotensin II, 5-L-isoleucine-, monoacetate (salt)
  • Asp-arg-val-tyr-ile-his-pro-phe acetate
  • Human angiotensin II acetate salt
  • UNII-31L3HS630A

Registry Numbers

CAS Registry Number

  • 32044-01-2

FDA UNII

  • 31L3HS630A

System Generated Number

  • 0032044012

Structure Descriptors

InChI

1S/C50H71N13O12.C2H4O2/c1-5-28(4)41(47(72)59-36(23-31-25-54-26-56-31)48(73)63-20-10-14-38(63)45(70)60-37(49(74)75)22-29-11-7-6-8-12-29)62-44(69)35(21-30-15-17-32(64)18-16-30)58-46(71)40(27(2)3)61-43(68)34(13-9-19-55-50(52)53)57-42(67)33(51)24-39(65)66;1-2(3)4/h6-8,11-12,15-18,25-28,33-38,40-41,64H,5,9-10,13-14,19-24,51H2,1-4H3,(H,54,56)(H,57,67)(H,58,71)(H,59,72)(H,60,70)(H,61,68)(H,62,69)(H,65,66)(H,74,75)(H4,52,53,55);1H3,(H,3,4)/t28-,33-,34-,35-,36-,37-,38-,40-,41-;/m0./s1

InChIKey

VBTZKFAHKJXHBA-PIONDTTLSA-N

Smiles

CC[C@H](C)[C@@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc3ccccc3)C(=O)O)NC(=O)[C@H](Cc4ccc(cc4)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)N.CC(=O)O