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Substance Name: Benserazide [USAN:INN:BAN]
RN: 322-35-0
UNII: 762OS3ZEJU
InChIKey: BNQDCRGUHNALGH-UHFFFAOYSA-N

Note

  • An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.

Molecular Formula

  • C10-H15-N3-O5

Molecular Weight

  • 257.245
 

Classification Codes

  • Anti-Dyskinesia Agents
  • Antiparkinson Agents
  • Antiparkinsonian
  • Central Nervous System Agents
  • Dopamine Agents
  • Drug / Therapeutic Agent
  • Enzyme Inhibitors
  • Inhibitor (Decarboxylase)
  • Neurotransmitter Agents
  • Reproductive Effect
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Names and Synonyms

Name of Substance

  • Benserazide
  • Benserazide [USAN:INN:BAN]

MeSH Heading

  • Benserazide

Synonyms

  • Benserazida
  • Benserazida [INN-Spanish]
  • Benserazide
  • Benserazidum
  • Benserazidum [INN-Latin]
  • BRN 3984490
  • DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
  • DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide
  • DL-Serine, 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
  • DL-Seryltrihydroxybenzylhydrazine
  • Ro 4-4602
  • Ro 44602
  • Serazide
  • UNII-762OS3ZEJU

Systematic Names

  • DL-Serine, 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
  • Serine, 2-(2,3,4-trihydroxybenzyl)hyrazide, DL-

Mixture Name

  • Madopa

Registry Numbers

CAS Registry Number

  • 322-35-0

FDA UNII

  • 762OS3ZEJU

System Generated Number

  • 0000322350

Structure Descriptors

InChI

1S/C10H15N3O5/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16/h1-2,6,12,14-17H,3-4,11H2,(H,13,18)

InChIKey

BNQDCRGUHNALGH-UHFFFAOYSA-N

Smiles

c1(c(c(c(O)cc1)O)O)CNNC([C@@H](CO)N)=O