Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Bunaftine [INN]
RN: 32421-46-8
UNII: GH09PRQ3FU
InChIKey: WWGZXRYELYWJBD-UHFFFAOYSA-N

Note

  • N-Butyl-N-(2-(diethylamino)ethyl)-1-naphthamide. A proposed antiarrhythmic that prolongs myocardial refractory period and stabilizes cell membranes.

Molecular Formula

  • C21-H30-N2-O

Molecular Weight

  • 326.481
 

Classification Codes

  • Anti-Arrhythmia Agents
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Bunaftine
  • Bunaftine [INN]

MeSH Heading

  • Bunaftine

Synonyms

  • BRN 2468082
  • Bunaftina
  • Bunaftina [INN-Spanish]
  • Bunaftine
  • Bunaftinum
  • Bunaftinum [INN-Latin]
  • Bunaphtide
  • Bunaphtine
  • EINECS 251-027-1
  • N-Butyl-N-(2-(diethylamino)ethyl)-1-naphthalenecarboxamide
  • N-Butyl-N-(2-(diethylamino)ethyl)-1-naphthamide
  • UNII-GH09PRQ3FU

Systematic Names

  • 1-Naphthalenecarboxamide, N-butyl-N-(2-(diethylamino)ethyl)-
  • Bunaftine
  • N-Butyl-N-(2-(diethylamino)ethyl)-1-naphthamide

Registry Numbers

CAS Registry Number

  • 32421-46-8

FDA UNII

  • GH09PRQ3FU

System Generated Number

  • 0032421468

Structure Descriptors

InChI

1S/C21H30N2O/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20/h8-14H,4-7,15-17H2,1-3H3

InChIKey

WWGZXRYELYWJBD-UHFFFAOYSA-N

Smiles

CCCCN(CCN(CC)CC)C(=O)c1cccc2c1cccc2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 122mg/kg (122mg/kg)   "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 226, 1989.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 4.060 (none)   EST
Atmospheric OH Rate Constant 1.41E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.