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Substance Name: Acecainide [INN]
RN: 32795-44-1
UNII: 910Q707V6F
InChIKey: KEECCEWTUVWFCV-UHFFFAOYSA-N

Note

  • A major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.

Molecular Formula

  • C15-H23-N3-O2

Molecular Weight

  • 277.366
 

Classification Codes

  • Anti-Arrhythmia Agents
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
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Names and Synonyms

Results Name

  • Acecainide [INN]

Name of Substance

  • Acecainide
  • Acecainide [INN]

MeSH Heading

  • Acecainide

Synonyms

  • 4'-((2-(Diethylamino)ethyl)carbamoyl)acetanilide
  • Acecainida
  • Acecainida [INN-Spanish]
  • Acecainide
  • Acecainidum
  • Acecainidum [INN-Latin]
  • Acekainid
  • Acekainid [Polish]
  • Benzamide, 4-(acetylamino)-N-(2-(diethylamino)ethyl)-
  • BRN 2868559
  • N-Acetyloprokainamid
  • N-Acetyloprokainamid [Polish]
  • N-Acetylprocainamide
  • NAPA
  • UNII-910Q707V6F

Systematic Names

  • Acetanilide, 4'-((2-(diethylamino)ethyl)carbamoyl)-
  • Benzamide, 4-(acetylamino)-N-(2-(diethylamino)ethyl)-

Registry Numbers

CAS Registry Number

  • 32795-44-1

FDA UNII

  • 910Q707V6F

Related Registry Number

  • 34118-92-8 (mono-hydrochloride)

System Generated Number

  • 0032795441

Structure Descriptors

InChI

1S/C15H23N3O2/c1-4-18(5-2)11-10-16-15(20)13-6-8-14(9-7-13)17-12(3)19/h6-9H,4-5,10-11H2,1-3H3,(H,16,20)(H,17,19)

InChIKey

KEECCEWTUVWFCV-UHFFFAOYSA-N

Smiles

N(C(=O)C)c1ccc(C(NCCN(CC)CC)=O)cc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 380mg/kg (380mg/kg) CARDIAC: OTHER CHANGES Proceedings of the Society for Experimental Biology and Medicine. Vol. 169, Pg. 156, 1982.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 0.990 (none)   EST
Atmospheric OH Rate Constant 1.16E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.