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Substance Name: 6-Aminonicotinamide
RN: 329-89-5
UNII: D6FNW67F2B
InChIKey: ZLWYEPMDOUQDBW-UHFFFAOYSA-N
Note
- A vitamin antagonist which has teratogenic effects.
Molecular Formula
- C6-H7-N3-O
Molecular Weight
- 137.141
Classification Codes
- Agricultural Chemical
- Drug / Therapeutic Agent
- Mutation Data
- Noxae
- Reproductive Effect
- Rodenticide
- Teratogens
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Names and Synonyms
Name of Substance
- 6-Aminonicotinamide
MeSH Heading
- 6-Aminonicotinamide
Synonyms
- 2-Amino-5-carbamoylpyridine
- 5-22-13-00618 (Beilstein Handbook Reference)
- 6-Aminonicotinamide
- 6-Aminonicotinic acid amide
- 6-Aminonikotinsaeureamid
- 6-Aminonikotinsaeureamid [German]
- AI3-50770
- BRN 0116042
- CCRIS 7679
- EINECS 206-349-7
- FDA 0121
- Nicotinamide, 6-amino-
- NSC 21206
- SR 4388
- U-8774
- UNII-D6FNW67F2B
Systematic Names
- 3-Pyridinecarboxamide, 6-amino-
- 6-Aminonicotinamide
- Nicotinamide, 6-amino- (8CI)
Registry Numbers
CAS Registry Number
- 329-89-5
FDA UNII
- D6FNW67F2B
System Generated Number
- 0000329895
Structure Descriptors
InChI
1S/C6H7N3O/c7-5-2-1-4(3-9-5)6(8)10/h1-3H,(H2,7,9)(H2,8,10)InChIKey
ZLWYEPMDOUQDBW-UHFFFAOYSA-NSmiles
c1(C(N)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | intraperitoneal | 10mg/kg (10mg/kg) | SENSE ORGANS AND SPECIAL SENSES: CHANGE IN ACUITY: EAR | Toxicology and Applied Pharmacology. Vol. 33, Pg. 320, 1975. |
| mouse | LD50 | intraperitoneal | 35mg/kg (35mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Canadian Patents. Vol. #1089763, |
| mouse | LDLo | oral | 320mg/kg (320mg/kg) | Archives of Environmental Contamination and Toxicology. Vol. 14, Pg. 111, 1985. | |
| rat | LD50 | intraperitoneal | 11mg/kg (11mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS | Canadian Patents. Vol. #1089763, |