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Substance Name: Cyclosarin
RN: 329-99-7
UNII: VM36F9N236
InChIKey: SNTRKUOVAPUGAY-UHFFFAOYSA-N

Note

  • Acetylcholinesterase inhibitor.

Molecular Formula

  • C7-H14-F-O2-P

Molecular Weight

  • 180.1576
 
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Names and Synonyms

Name of Substance

  • Cyclohexyl methylphosphonofluoridate
  • Cyclosarin

Synonyms

  • BRN 2327087
  • CF Me ester
  • CMPF
  • Cyclohexyl methylphosphonofluoridate
  • Cyclosarin
  • Cyclosin
  • Cyclosin (chemical warfare agent)
  • EA 1212
  • GF
  • GF (chemical warfare agent)
  • HSDB 7597
  • Methyl cyclohexylfluorophosphonate
  • O-Cyclohexyl methylphosphonofluoridate
  • UNII-VM36F9N236

Systematic Name

  • Phosphonofluoridic acid, methyl-, cyclohexyl ester

Registry Numbers

CAS Registry Number

  • 329-99-7

FDA UNII

  • VM36F9N236

Other Registry Numbers

  • 38184-40-6
  • 74192-15-7

System Generated Number

  • 0000329997

Structure Descriptors

InChI

1S/C7H14FO2P/c1-11(8,9)10-7-5-3-2-4-6-7/h7H,2-6H2,1H3

InChIKey

SNTRKUOVAPUGAY-UHFFFAOYSA-N

Smiles

CP(=O)(OC1CCCCC1)F

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 subcutaneous 100ug/kg (0.1mg/kg)   Canadian Journal of Physiology and Pharmacology. Vol. 44, Pg. 745, 1966.
hamster LD50 subcutaneous 130ug/kg (0.13mg/kg)   Canadian Journal of Physiology and Pharmacology. Vol. 46, Pg. 109, 1968.
mouse LD50 subcutaneous 400ug/kg (0.4mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: COMA

GASTROINTESTINAL: NAUSEA OR VOMITING
Science Journal. Vol. 3(4), Pg. 33, 1967.
rabbit LD50 subcutaneous 100ug/kg (0.1mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: COMA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Science Journal. Vol. 3(4), Pg. 33, 1967.
rat LD50 intramuscular 80ug/kg (0.08mg/kg)   Pharmacology and Toxicology Vol. 84, Pg. 41, 1999.
rat LD50 subcutaneous 225ug/kg (0.225mg/kg)   Canadian Journal of Physiology and Pharmacology. Vol. 44, Pg. 745, 1966.