|
|
Substance Name: Proroxan hydrochloride [USAN]
RN: 33025-33-1
UNII: 694Z9P44G4
InChIKey: QQZPGRDQMBPRFY-UHFFFAOYSA-N
Classification Codes
- Anti-Adrenergic (alpha-Receptor)
- Drug / Therapeutic Agent
Molecular Formula
- C21-H23-N-O3.Cl-H
Molecular Weight
- 373.878
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Name of Substance
- Proroxan hydrochloride [USAN]
Synonyms
- 1-(1,4-Benzodioxan-6-yl)-3-(3-phenyl-1-pyrrolidinyl)-1-propanone hydrochloride
- 6-(3-(3-Phenylpyrrolidinyl)propionyl)-1,4-benzodioxan, hydrochloride
- AY 24,269
- AY-24,269
- Pirroksan
- Proroxan HCl
- Proroxan hydrochloride
- Pyrroxane
- UNII-694Z9P44G4
Systematic Names
- 1,4-Benzodioxan, 6-(3-(3-phenylpyrrolidinyl)propionyl)-, hydrochloride
- 1-Propanone, 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3-phenyl-1-pyrrolidinyl)-, hydrochloride
Registry Numbers
CAS Registry Number
- 33025-33-1
FDA UNII
- 694Z9P44G4
Related Registry Number
- 33743-96-3 (Parent)
System Generated Number
- 0033025331
Molecular Formulas
Molecular Formula
- C21-H23-N-O3.Cl-H
Molecular Formula Fragments
- C21-H23-N-O3
- Cl-H
- COMPONENT
Structure Descriptors
InChI
InChI=1S/C21H23NO3.ClH/c23-19(17-6-7-20-21(14-17)25-13-12-24-20)9-11-22-10-8-18(15-22)16-4-2-1-3-5-16;/h1-7,14,18H,8-13,15H2;1HInChIKey
QQZPGRDQMBPRFY-UHFFFAOYSA-NSmiles
Cl.O=C(CCN1CCC(C1)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 140mg/kg (140mg/kg) | Russian Pharmacology and Toxicology Vol. 36, Pg. 172, 1973. | |
rat | LD50 | intraperitoneal | 100mg/kg (100mg/kg) | Russian Pharmacology and Toxicology Vol. 36, Pg. 172, 1973. |