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Substance Name: Avanafil [USAN:INN]
RN: 330784-47-9
UNII: DR5S136IVO
InChIKey: WEAJZXNPAWBCOA-INIZCTEOSA-N

Note

  • A PDE5 inhibitor.

Classification Code

  • Treatment of Erectile Dysfunction

Molecular Formula

  • C23-H26-Cl-N7-O3

Molecular Weight

  • 483.9574
 

Names and Synonyms

Name of Substance

  • Avanafil [USAN:INN]

Synonyms

  • (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamide
  • 4-((3-Chloro-4-methoxybenzyl)amino)-2-((2S)-2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
  • 5-Pyrimidinecarboxamide, 4-(((3-chloro-4-methoxyphenyl)methyl)amino)-2-((2S)-2-(hydroxymethyl)-1-pyrrolidinyl)-N-(2-pyrimidinylmethyl)-
  • Avanafil
  • Stendra
  • TA 1790
  • TA-1790
  • UNII-DR5S136IVO

Systematic Name

  • 5-Pyrimidinecarboxamide, 4-(((3-chloro-4-methoxyphenyl)methyl)amino)-2-((2S)-2-(hydroxymethyl)-1-pyrrolidinyl)-N-(2-pyrimidinylmethyl)-

Registry Numbers

CAS Registry Number

  • 330784-47-9

FDA UNII

  • DR5S136IVO

Other Registry Numbers

  • 330785-17-6
  • 647841-09-6

System Generated Number

  • 0330784479

Structure Descriptors

InChI

1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3,5-8,10,12,16,32H,2,4,9,11,13-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m0/s1

InChIKey

WEAJZXNPAWBCOA-INIZCTEOSA-N

Smiles

c1c(c(cc(c1)CNc1nc(ncc1C(=O)NCc1ncccn1)N1CCC[C@H]1CO)Cl)OC