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Substance Name: Humanin
RN: 330936-69-1
InChIKey: DPEUWKZJZIPZKE-OFANTOPUSA-N

Note

  • Suppresses neuronal cell death induced by the Swedish mutant of amyloid precursor protein; suppresses neuronal cell death induced by three different types of FAD genes and amyloid beta; amino acid sequence in first source

Classification Code

  • Peptides

Molecular Formula

  • C119-H204-N34-O32-S2

Molecular Weight

  • 2687.26
 
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Names and Synonyms

Name of Substance

  • Humanin

Synonyms

  • 1-24-Protein humanin (human)
  • Protein (human clone 1 humanin sequence homolog)
  • Protein Humanin (human)
  • T lymphocyte activation-associated protein PRO86272 (human)

Systematic Name

  • L-Alanine, L-methionyl-L-alanyl-L-prolyl-L-arginylglycyl-L-phenylalanyl-L-seryl-L-cysteinyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonyl-L-seryl-L- alpha-glutamyl-L-isoleucyl-L-alpha-aspartyl-L-leucyl-L-prolyl-L-valyl-L-lysyl-L-arginyl-L-arginyl-

Registry Numbers

CAS Registry Number

  • 330936-69-1

System Generated Number

  • 0330936691

Structure Descriptors

InChI

1S/C119H204N34O32S2/c1-19-65(14)92(112(180)144-81(54-90(160)161)104(172)145-82(52-63(10)11)115(183)153-46-29-37-87(153)110(178)149-91(64(12)13)111(179)139-72(32-23-24-41-120)97(165)136-74(35-27-44-130-119(126)127)98(166)135-73(34-26-43-129-118(124)125)96(164)133-67(16)116(184)185)150-99(167)75(38-39-89(158)159)137-106(174)84(57-155)147-113(181)93(68(17)156)151-105(173)79(51-62(8)9)142-101(169)77(49-60(4)5)140-100(168)76(48-59(2)3)141-102(170)78(50-61(6)7)143-108(176)85(58-186)148-107(175)83(56-154)146-103(171)80(53-69-30-21-20-22-31-69)134-88(157)55-131-95(163)71(33-25-42-128-117(122)123)138-109(177)86-36-28-45-152(86)114(182)66(15)132-94(162)70(121)40-47-187-18/h20-22,30-31,59-68,70-87,91-93,154-156,186H,19,23-29,32-58,120-121H2,1-18H3,(H,131,163)(H,132,162)(H,133,164)(H,134,157)(H,135,166)(H,136,165)(H,137,174)(H,138,177)(H,139,179)(H,140,168)(H,141,170)(H,142,169)(H,143,176)(H,144,180)(H,145,172)(H,146,171)(H,147,181)(H,148,175)(H,149,178)(H,150,167)(H,151,173)(H,158,159)(H,160,161)(H,184,185)(H4,122,123,128)(H4,124,125,129)(H4,126,127,130)/t65-,66-,67-,68+,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,91-,92-,93-/m0/s1

InChIKey

DPEUWKZJZIPZKE-OFANTOPUSA-N

Smiles

N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(O)=O)C)CCCNC(N)=N)CCCNC(N)=N)CCCCN)C(C)C)CCC2)CC(C)C)CC(=O)O)[C@@H](C)CC)CCC(=O)O)CO)[C@H](O)C)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)CS)=O)CO)Cc2ccccc2)CCCNC(N)=N)=O)CCC1)=O)C)=O)CCSC