Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: k-Strophanthoside
RN: 33279-57-1
UNII: 8141H9654J
InChIKey: GILGYKHFZXQALF-FBPIOBPTSA-N

Note

  • Cardiac glycoside extracted from Strophanthus kombe; sugars (glucose-glucose-cymarose) are bonded with strophanthidin.

Molecular Formula

  • C42-H64-O19

Molecular Weight

  • 872.9486
 

Classification Code

  • Natural Product
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • k-Strophanthoside

Synonyms

  • EINECS 251-439-1
  • k-Strofantozyd
  • k-Strofantozyd [Polish]
  • k-Strophanthidin-gamma
  • k-Strophanthoside
  • k-Strophantosid
  • k-Strophantosid [German]
  • k-Strophantoside
  • NSC 7530
  • Strophanthidin + cymarose + beta-glucose + alpha-glucose
  • Strophanthidin + cymarose + beta-glucose + alpha-glucose [German]
  • UNII-8141H9654J

Systematic Names

  • (3beta,5beta)-3-((O-beta-D-glucopyranosyl-(1.6)-O-beta-D-glucopyranosyl-(1.4)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)-5,14-dihydroxy-19-oxocard-20(22)-enolide
  • 5-beta-Card-20(22)-enolide, 3-beta-((O-beta-D-glucopyranosyl-(1-6)-O-beta-D-glucopyranosyl-(1-4)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)-5,14-dihydroxy-19-oxo-
  • Card-20(22)-enolide, 3-((O-beta-D-glucopyranosyl-(1-6)-O-beta-D-glucopyranosyl-(1-4)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)- (9CI)

Registry Numbers

CAS Registry Number

  • 33279-57-1

FDA UNII

  • 8141H9654J

Other Registry Numbers

  • 12627-24-6
  • 12773-28-3
  • 29008-41-1

System Generated Number

  • 0033279571

Structure Descriptors

InChI

1S/C42H64O19/c1-19-36(61-38-35(51)33(49)31(47)27(60-38)17-56-37-34(50)32(48)30(46)26(15-43)59-37)25(54-3)13-29(57-19)58-21-4-9-40(18-44)23-5-8-39(2)22(20-12-28(45)55-16-20)7-11-42(39,53)24(23)6-10-41(40,52)14-21/h12,18-19,21-27,29-38,43,46-53H,4-11,13-17H2,1-3H3/t19-,21+,22-,23+,24-,25+,26-,27-,29+,30-,31-,32+,33+,34-,35-,36-,37-,38+,39-,40+,41+,42+/m1/s1

InChIKey

GILGYKHFZXQALF-FBPIOBPTSA-N

Smiles

CO[C@H]1C[C@H](O[C@H]2CC[C@]3(C=O)[C@H]4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)O[C@H](C)[C@H]1O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 intravenous 130ug/kg (0.13mg/kg)   "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 194, 1963.
cat LDLo oral 5mg/kg (5mg/kg)   Farmacognosia. Vol. 13, Pg. 375, 1953.
cat LDLo parenteral 1900ug/kg (1.9mg/kg)   Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 34, Pg. 431, 1977.
cat LDLo unreported 187ug/kg (0.187mg/kg)   "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 124, 1963.
mammal (species unspecified) LDLo intraperitoneal 550ug/kg (0.55mg/kg)   Acta Pharmaceutica Jugoslavica. Vol. 24, Pg. 179, 1974.
mammal (species unspecified) LDLo intravenous 240ug/kg (0.24mg/kg)   Acta Pharmaceutica Jugoslavica. Vol. 24, Pg. 179, 1974.
mouse LD50 intracrebral 34ug/kg (0.034mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 908, 1961.
mouse LD50 intravenous 8161ug/kg (8.161mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 908, 1961.