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Substance Name: Pyrantel tartrate [USAN]
RN: 33401-94-4
UNII: SC82VF0480
InChIKey: VWRCYAZJKNPEQR-NIEARKAZSA-N

Note

  • Broad spectrum anthelmintic for livestock.

Molecular Formula

  • C11-H14-N2-S.C4-H6-O6

Molecular Weight

  • 356.397
 

Classification Codes

  • Anthelmintic
  • Anthelmintics
  • Anti-Infective Agents
  • Antinematodal Agents
  • Antiparasitic Agents
  • Drug / Therapeutic Agent
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Names and Synonyms

Name of Substance

  • Pyrantel tartrate
  • Pyrantel tartrate [USAN]

MeSH Heading

  • Pyrantel tartrate

Synonyms

  • (E)-1,4,5,6-Tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine tartrate (1:1)
  • Banminth
  • Banminth 48
  • CP 10423-18
  • CP-10,423-18
  • EINECS 251-501-8
  • Pyrantel tartrate
  • Pyrequan tartrate
  • UNII-SC82VF0480

Systematic Names

  • Pyrantel hydrogen tartrate
  • Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)-, (E)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1)
  • Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)-, (E)-, tartrate (1:1)

Registry Numbers

CAS Registry Number

  • 33401-94-4

FDA UNII

  • SC82VF0480

Other Registry Numbers

  • 7085-69-0
  • 7635-10-1

System Generated Number

  • 0033401944

Molecular Formulas

Molecular Formula

  • C11-H14-N2-S.C4-H6-O6

Molecular Formula Fragments

  • C11-H14-N2-S
  • C4-H6-O6
  • COMPONENT

Structure Descriptors

InChI

1S/C11H14N2S.C4H6O6/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10;5-1(3(7)8)2(6)4(9)10/h2,4-6,9H,3,7-8H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/b6-5+;/t;1-,2-/m.1/s1

InChIKey

VWRCYAZJKNPEQR-NIEARKAZSA-N

Smiles

CN1CCCN=C1/C=C/c2cccs2.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cattle LD unreported > 200mg/kg (200mg/kg)   Australian Veterinary Journal. Vol. 46, Pg. 297, 1970.
mouse LD50 intravenous 2220ug/kg (2.22mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
mouse LD50 oral 123mg/kg (123mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
mouse LD50 subcutaneous > 25mg/kg (25mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
rat LD50 oral 170mg/kg (170mg/kg)   Australian Veterinary Journal. Vol. 46, Pg. 297, 1970.