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Substance Name: Diflorasone diacetate [USAN:USP:JAN]
RN: 33564-31-7
UNII: 7W2J09SCWX
InChIKey: BOBLHFUVNSFZPJ-JOYXJVLSSA-N
Classification Codes
- Anti-Inflammatory (Topical)
- Hormone
- Reproductive Effect
Molecular Formula
- C26-H32-F2-O7
Molecular Weight
- 494.5278
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Names and Synonyms
Name of Substance
- Diflorasone diacetate
- Diflorasone diacetate [USAN:USP:JAN]
Synonyms
- 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-diacetate
- Apexicon
- Apexicon e
- BRN 2318163
- Diflorasone diacetate
- EINECS 251-575-1
- Florone
- Florone E
- Maxiflor
- Psorcon
- Psorcon E
- U 34865
- U-34,865
- UNII-7W2J09SCWX
Systematic Names
- 6alpha-Fluorobetamethasone-17,21 diacetate
- Diflorasone di(acetate)
- Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-, (6alpha,11beta,16beta)-
Registry Numbers
CAS Registry Number
- 33564-31-7
FDA UNII
- 7W2J09SCWX
System Generated Number
- 0033564317
Structure Descriptors
InChI
InChI=1S/C26H32F2O7/c1-13-8-17-18-10-20(27)19-9-16(31)6-7-23(19,4)25(18,28)21(32)11-24(17,5)26(13,35-15(3)30)22(33)12-34-14(2)29/h6-7,9,13,17-18,20-21,32H,8,10-12H2,1-5H3/t13-,17-,18-,20-,21-,23-,24-,25-,26-/m0/s1InChIKey
BOBLHFUVNSFZPJ-JOYXJVLSSA-NSmiles
C[C@H]1C[C@H]2[C@@H]3C[C@H](F)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | > 3gm/kg (3000mg/kg) | Drugs in Japan Vol. -, Pg. 487, 1990. | |
mouse | LD50 | oral | > 3gm/kg (3000mg/kg) | Drugs in Japan Vol. -, Pg. 487, 1990. | |
mouse | LD50 | subcutaneous | > 3gm/kg (3000mg/kg) | Drugs in Japan Vol. -, Pg. 487, 1990. | |
rat | LD50 | intraperitoneal | > 3gm/kg (3000mg/kg) | Drugs in Japan Vol. -, Pg. 487, 1990. | |
rat | LD50 | oral | > 3gm/kg (3000mg/kg) | Drugs in Japan Vol. -, Pg. 487, 1990. | |
rat | LD50 | subcutaneous | > 3gm/kg (3000mg/kg) | Drugs in Japan Vol. -, Pg. 487, 1990. |