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Substance Name: Levcycloserine [USAN:INN]
RN: 339-72-0
UNII: AK7DRB7FMO
InChIKey: DYDCUQKUCUHJBH-REOHCLBHSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Enzyme Inhibitor (Gaucher's Disease)
  • Enzyme Inhibitor (Gauchers Disease)

Molecular Formula

  • C3-H6-N2-O2

Molecular Weight

  • 102.0924
 
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Names and Synonyms

Name of Substance

  • Levcycloserine [USAN:INN]

Synonyms

  • (-)-4-Amino-3-isossazolidone
  • (-)-4-Amino-3-isossazolidone [Italian]
  • (S)-(-)-Cycloserine
  • (S)-4-Amino-3-isoxazolidinone
  • 4-27-00-05550 (Beilstein Handbook Reference)
  • BRN 0080799
  • Cyclo-L-serine
  • EINECS 206-427-0
  • L-4-Amino-3-isoxazolidinone
  • L-Cycloserine
  • L-Oxamicina
  • L-Oxamicina [Italian]
  • Levcicloserina
  • Levcicloserina [INN-Spanish]
  • Levcycloserine
  • Levcycloserinum
  • Levcycloserinum [INN-Latin]
  • UNII-AK7DRB7FMO

Systematic Names

  • 3-Isoxazolidinone, 4-amino-, (L)-
  • 3-Isoxazolidinone, 4-amino-, (S)-
  • L-4-Aminoisoxazolidin-3-one

Registry Numbers

CAS Registry Number

  • 339-72-0

FDA UNII

  • AK7DRB7FMO

Other Registry Number

  • 433-56-7

System Generated Number

  • 0000339720

Structure Descriptors

InChI

1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m0/s1

InChIKey

DYDCUQKUCUHJBH-REOHCLBHSA-N

Smiles

N[C@H]1CONC1=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1889mg/kg (1889mg/kg)   Neuropharmacology. Vol. 25, Pg. 411, 1986.
mouse LD50 intravenous 1071mg/kg (1071mg/kg)   Neuropharmacology. Vol. 25, Pg. 411, 1986.
mouse LD50 oral 2492mg/kg (2492mg/kg)   Neuropharmacology. Vol. 25, Pg. 411, 1986.
rat LDLo intraperitoneal 1gm/kg (1000mg/kg)   Neuropharmacology. Vol. 25, Pg. 411, 1986.
rat LDLo intravenous 500mg/kg (500mg/kg)   Neuropharmacology. Vol. 25, Pg. 411, 1986.
rat LDLo oral 2gm/kg (2000mg/kg)   Neuropharmacology. Vol. 25, Pg. 411, 1986.