Substance Name: Panitumumab [USAN:INN:BAN]
RN: 339177-26-3
UNII: 6A901E312A
Notes
- Antibody that blocks receptors for epidermal growth factor; approved for advanced colon cancer.
- Recombinant human monoclonal antibody that binds to and inhibits the function of the EPIDERMAL GROWTH FACTOR RECEPTOR. It is used in the treatment of EGFR-expressing metastatic colorectal cancer that expresses wild-type ras gene (see GENES, RAS).
Molecular Formulas
- C6306-H9732-N1672-O1994-S46
- Unspecified
Classification Codes
- Antineoplastic
- Antineoplastic Agents
- Antineoplastic Agents, Immunological
- Treatment of EGF Expressing Tumors
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Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- Panitumumab
- Panitumumab [USAN:INN:BAN]
MeSH Heading
- Panitumumab
Synonyms
- Abenix
- ABX-EGF
- ABX-EGF MAb
- Monoclonal antibody ABX-EGF
- NSC 742319
- Panitumumab
- Panitumumab (genetical recombination)
- UNII-6A901E312A
- Vectibix
Systematic Names
- ABX-EGF
- Immunoglobulin, anti-(human epidermal growth factor receptor) (human monoclonal ABX-EGF heavy chain), disulfide with human monoclonal ABX-EGF light chain, dimer
- Immunoglobulin, human (anti-human epidermal growth factor receptor) monoclonal antibody (ABX-EGF)
Registry Numbers
CAS Registry Number
- 339177-26-3
FDA UNII
- 6A901E312A
System Generated Number
- 0339177263