Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Tripterine
RN: 34157-83-0
UNII: L8GG98663L
InChIKey: KQJSQWZMSAGSHN-JJWQIEBTSA-N

Note

  • Isolated from Tripterygium wilfordii; potent inhibitory activity on both Kir2.1 and ERG1 potassium channels, leading to LONG QT SYNDROME.

Molecular Formula

  • C29-H38-O4

Molecular Weight

  • 450.6152
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Tripterine

Synonyms

  • Celastrol
  • NSC 70931
  • UNII-L8GG98663L

Systematic Name

  • D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, (20alpha)-

Registry Numbers

CAS Registry Number

  • 34157-83-0

FDA UNII

  • L8GG98663L

System Generated Number

  • 0034157830

Structure Descriptors

InChI

1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1

InChIKey

KQJSQWZMSAGSHN-JJWQIEBTSA-N

Smiles

C12=CC(=O)C(=C(C2=CC=C2[C@]1(CC[C@@]1([C@@]2(CC[C@@]2([C@H]1C[C@](C(=O)O)(CC2)C)C)C)C)C)C)O