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Substance Name: Glymidine sodium [USAN:INN:BAN:JAN]
RN: 3459-20-9
UNII: QPY3C057X1
InChIKey: NUQDEHHKOXSIEA-UHFFFAOYSA-N

Note

  • A sulfonamide hypoglycemic agent which stimulates insulin secretion.

Molecular Formulas

  • C13-H14-N3-Na-O4-S
  • C13-H14-N3-O4-S.Na
  • C13-H15-N3-O4-S.Na

Molecular Weight

  • 331.3266
 

Classification Codes

  • Antidiabetic
  • Drug / Therapeutic Agent
  • Reproductive Effect
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Names and Synonyms

Name of Substance

  • Glymidine sodium salt
  • Glymidine sodium [USAN:INN:BAN:JAN]

Synonyms

  • (N-(5-(2-Methoxyethoxy)-2-pyrimidinyl)benzenesulfonamido) sodium salt
  • 2-Benzenesulfonamido-5-(beta-methoxyethoxy)pyrimidine sodium salt
  • Benzenesulfonamide, N-(5-(2-methoxyethoxy)-2-pyrimidinyl)-, sodium salt
  • EINECS 222-399-2
  • Glimidina sodica
  • Glimidina sodica [INN-Spanish]
  • Glycanol
  • Glycodiazin
  • Glycodiazine
  • Glycodiazine sodium
  • Glycodiazine sodium salt
  • Glyconormal
  • Glymidine
  • Glymidine sodique
  • Glymidine sodique [INN-French]
  • Glymidine sodium
  • Glymidine sodium salt
  • Glymidinum natricum
  • Glymidinum natricum [INN-Latin]
  • Gondafon
  • Lycanol
  • N-(5-(2-Methoxyethoxy)-2-pyrimidinyl)benzenesulfonamide sodium
  • N-(5-(2-Methoxyethoxy)-2-pyrimidinyl)benzenesulfonamide sodium salt
  • Redul
  • Redul IF
  • Redul sodium
  • SH 717
  • Sodium 2-benzenesulphonylamino-5-(2-methoxyethoxy)pyrimidine
  • Sodium benzenesulfonamide, N-(5-(2-methoxyethoxy)-2-pyrimidinyl)-
  • Sodium glycodiazine
  • Sodium glymidine
  • UNII-QPY3C057X1

Systematic Names

  • Benzenesulfonamide, N-(5-(2-methoxyethoxy)-2-pyrimidinyl)-, sodium salt
  • Glymidine sodium

Registry Numbers

CAS Registry Number

  • 3459-20-9

FDA UNII

  • QPY3C057X1

System Generated Number

  • 0003459209

Molecular Formulas

Molecular Formulas

  • C13-H14-N3-Na-O4-S
  • C13-H14-N3-O4-S.Na
  • C13-H15-N3-O4-S.Na

Molecular Formula Fragments

  • C13-H14-N3-O4-S
  • C13-H15-N3-O4-S
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C13H14N3O4S.Na/c1-19-7-8-20-11-9-14-13(15-10-11)16-21(17,18)12-5-3-2-4-6-12;/h2-6,9-10H,7-8H2,1H3;/q-1;+1

InChIKey

NUQDEHHKOXSIEA-UHFFFAOYSA-N

Smiles

COCCOc1cnc(nc1)[N-]S(=O)(=O)c2ccccc2.[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 3210mg/kg (3210mg/kg)   Drugs in Japan Vol. 6, Pg. 221, 1982.
mouse LD50 intravenous 1480mg/kg (1480mg/kg) ENDOCRINE: HYPOGLYCEMIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR
Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 377, 1964.
mouse LD50 oral 5300mg/kg (5300mg/kg) BEHAVIORAL: TREMOR

ENDOCRINE: HYPOGLYCEMIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 377, 1964.
mouse LD50 subcutaneous 3340mg/kg (3340mg/kg)   Drugs in Japan Vol. 6, Pg. 221, 1982.
rat LD50 intraperitoneal 3120mg/kg (3120mg/kg)   Drugs in Japan Vol. 6, Pg. 221, 1982.
rat LD50 intravenous 2gm/kg (2000mg/kg) BEHAVIORAL: TREMOR

ENDOCRINE: HYPOGLYCEMIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 377, 1964.
rat LD50 oral 2850mg/kg (2850mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR

ENDOCRINE: HYPOGLYCEMIA
Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 377, 1964.
rat LD50 subcutaneous 2800mg/kg (2800mg/kg)   Drugs in Japan Vol. 6, Pg. 221, 1982.