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Substance Name: Fenoprofen sodium
RN: 34691-31-1
UNII: 869607J16Q
InChIKey: WVKIYGXHDKTNFO-UHFFFAOYSA-M

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C15-H13-O3.Na

Molecular Weight

  • 264.255
 
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Names and Synonyms

Name of Substance

  • Fenoprofen sodium

Synonyms

  • d,l-2-(3-Phenoxyphenyl)propionic acid, sodium salt
  • Fenoprofen sodium
  • UNII-869607J16Q

Systematic Name

  • Propionic acid, 2-(3-phenoxyphenyl)-, sodium salt, (+-)-

Registry Numbers

CAS Registry Number

  • 34691-31-1

FDA UNII

  • 869607J16Q

System Generated Number

  • 0034691311

Molecular Formulas

Molecular Formula

  • C15-H13-O3.Na

Molecular Formula Fragments

  • C15-H13-O3
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C15H14O3.Na/c1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13;/h2-11H,1H3,(H,16,17);/q;+1/p-1

InChIKey

WVKIYGXHDKTNFO-UHFFFAOYSA-M

Smiles

c1(cc(ccc1)[C@@H](C([O-])=O)C)Oc1ccccc1.[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD intravenous > 100mg/kg (100mg/kg)   Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 183, 1977.
dog LD oral > 200mg/kg (200mg/kg)   Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 183, 1977.
mouse LD50 intraperitoneal 286mg/kg (286mg/kg) GASTROINTESTINAL: PERITONITIS Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980.
mouse LD50 intravenous 471mg/kg (471mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980.
mouse LD50 subcutaneous 463mg/kg (463mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980.
rat LD50 intraperitoneal 234mg/kg (234mg/kg) GASTROINTESTINAL: OTHER CHANGES Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980.
rat LD50 intravenous 500mg/kg (500mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Toxicology and Applied Pharmacology. Vol. 25, Pg. 444, 1973.
rat LD50 oral 800mg/kg (800mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Toxicology and Applied Pharmacology. Vol. 25, Pg. 444, 1973.
rat LD50 subcutaneous 500mg/kg (500mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 25, Pg. 444, 1973.