Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Carbuterol hydrochloride [USAN]
RN: 34866-46-1
UNII: G8F3U654FU
InChIKey: QHWYYBXPBFQGNI-UHFFFAOYSA-N

Classification Codes

  • Bronchodilator
  • Drug / Therapeutic Agent

Molecular Formula

  • C13-H21-N3-O3.Cl-H

Molecular Weight

  • 303.7878
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Carbuterol hydrochloride
  • Carbuterol hydrochloride [USAN]

Synonyms

  • (5-(2-(t-Butylamino)-1-hydroxyethyl)-2-hydroxyphenyl)urea hydrochloride
  • (5-(2-(tert-Butylamino)-1-hydroxyethyl)-2-hydroxyphenyl)urea monohydrochloride
  • Bronsecur
  • Carbuterol HCl
  • Carbuterol hydrochloride
  • CCRIS 1087
  • EINECS 252-255-4
  • Phenol, 4-(2-tert-butylamino-1-hydroxy)ethyl-2-ureido-, hydrochloride
  • SK&F 40383
  • SKF 40383
  • UNII-G8F3U654FU
  • Urea, (5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-2-hydroxyphenyl)-, monohydrochloride

Systematic Names

  • (5-(2-((tert-Butyl)amino)-1-hydroxyethyl)-2-hydroxyphenyl)uronium chloride
  • Carbuterol hydrochloride
  • Urea, (5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-2-hydroxyphenyl)-, monohydrochloride
  • Urea, 1-(5-((2'-t-butylamino-1'-hydroxy)ethyl)-2-hydroxyphenyl)-, hydrochloride

Registry Numbers

CAS Registry Number

  • 34866-46-1

FDA UNII

  • G8F3U654FU

Other Registry Number

  • 51395-50-7

Related Registry Number

  • 34866-47-2 (Parent)

System Generated Number

  • 0034866461

Molecular Formulas

Molecular Formula

  • C13-H21-N3-O3.Cl-H

Molecular Formula Fragments

  • C13-H21-N3-O3
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C13H21N3O3.ClH/c1-13(2,3)15-7-11(18)8-4-5-10(17)9(6-8)16-12(14)19;/h4-6,11,15,17-18H,7H2,1-3H3,(H3,14,16,19);1H

InChIKey

QHWYYBXPBFQGNI-UHFFFAOYSA-N

Smiles

CC(C)(C)NCC(c1ccc(c(c1)NC(=O)N)O)O.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 2040mg/kg (2040mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Journal of Pharmacology and Experimental Therapeutics. Vol. 189, Pg. 167, 1974.
guinea pig LD50 subcutaneous 473mg/kg (473mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

SKIN AND APPENDAGES (SKIN): HAIR: OTHER

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Journal of Pharmacology and Experimental Therapeutics. Vol. 189, Pg. 167, 1974.
mouse LD50 intravenous 37mg/kg (37mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Journal of Pharmacology and Experimental Therapeutics. Vol. 189, Pg. 167, 1974.
mouse LD50 oral 3543mg/kg (3543mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Journal of Pharmacology and Experimental Therapeutics. Vol. 189, Pg. 167, 1974.
rat LD50 intravenous 87mg/kg (87mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Journal of Pharmacology and Experimental Therapeutics. Vol. 189, Pg. 167, 1974.
rat LDLo oral 8gm/kg (8000mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
Journal of Pharmacology and Experimental Therapeutics. Vol. 189, Pg. 167, 1974.