Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Carbinoxamine maleate [USP:JAN]
RN: 3505-38-2
UNII: 02O55696WH
InChIKey: GVNWHCVWDRNXAZ-BTJKTKAUSA-N

Classification Codes

  • Antihistaminic
  • Drug / Therapeutic Agent
  • Histamine Agents
  • Histamine Antagonists
  • Histamine H1 Antagonists
  • Human Data
  • Neurotransmitter Agents

Molecular Formula

  • C16-H19-Cl-N2-O.C4-H4-O4

Molecular Weight

  • 406.8637
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Carbinoxamine maleate [USP:JAN]

Synonyms

  • 2-(p-Chloro-alpha-(2-(dimethylamino)ethoxy)benzyl)pyridine bimaleate
  • 2-(p-Chloro-alpha-(2-(dimethylamino)ethoxy)benzyl)pyridine maleate
  • 2-(p-Chloro-alpha-(2-(dimethylamino)ethoxy)benzyl)pyridine maleate (1:1)
  • Allergefon
  • Allergefon maleate
  • Arbinoxa
  • Carbinoxamine maleate
  • Ciberon
  • Clistin
  • Cliston
  • EINECS 222-498-0
  • Ethanamine, 2-((4-chlorophenyl)-2-pyridinylmethoxy)-N,N-dimethyl-, (Z)-2-butenedioate (1:1)
  • Hislosine
  • Histine sirup
  • Karbinal ER
  • Lergefin
  • NSC 62362
  • p-Carbinoxamine maleate
  • Paracarbinoxamine maleate
  • Polistin T-caps
  • Polistine T-caps
  • Rondec
  • Rondec DM
  • UNII-02O55696WH
  • Ziriton

Systematic Names

  • Carbinoxamine hydrogen maleate
  • Ethanamine, 2-((4-chlorophenyl)-2-pyridinylmethoxy)-N,N-dimethyl-, (2Z)-2-butenedioate (1:1)
  • Ethanamine, 2-((4-chlorophenyl)-2-pyridinylmethoxy)-N,N-dimethyl-, (Z)-2-butenedioate (1:1)
  • Pyridine, 2-(p-chloro-alpha-(2-(dimethylamino)ethoxy)benzyl)-, maleate (1:1)

Mixture Name

  • Clistin-D

Registry Numbers

CAS Registry Number

  • 3505-38-2

FDA UNII

  • 02O55696WH

Other Registry Number

  • 121366-99-2

Related Registry Number

  • 486-16-8 (Parent)

System Generated Number

  • 0003505382

Molecular Formulas

Molecular Formula

  • C16-H19-Cl-N2-O.C4-H4-O4

Molecular Formula Fragments

  • C16-H19-Cl-N2-O
  • C4-H4-O4
  • COMPONENT

Structure Descriptors

InChI

1S/C16H19ClN2O.C4H4O4/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-10,16H,11-12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChIKey

GVNWHCVWDRNXAZ-BTJKTKAUSA-N

Smiles

CN(C)CCOC(c1ccc(cc1)Cl)c2ccccn2.C(=C\C(=O)O)\C(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo oral 1880ug/kg/4D- (1.88mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

BEHAVIORAL: EXCITEMENT
Journal of Toxicology, Clinical Toxicology. Vol. 25, Pg. 161, 1987.
dog LDLo intravenous 36mg/kg (36mg/kg)   Compilation of LD50 Values of New Drugs.
guinea pig LD50 oral 411mg/kg (411mg/kg)   Compilation of LD50 Values of New Drugs.
guinea pig LD50 subcutaneous 120mg/kg (120mg/kg)   Annales Pharmaceutiques Francaises. Vol. 20, Pg. 463, 1962.
mouse LD50 intraperitoneal 150mg/kg (150mg/kg)   Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 15, Pg. 367, 1968.
mouse LD50 intravenous 32mg/kg (32mg/kg)   Compilation of LD50 Values of New Drugs.
mouse LD50 oral 162mg/kg (162mg/kg)   Compilation of LD50 Values of New Drugs.
mouse LD50 subcutaneous 350mg/kg (350mg/kg)   Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 15, Pg. 367, 1968.