Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Prajmalium
RN: 35080-11-6
UNII: 75934UD4GJ
InChIKey: UAUHEPXILIZYCU-ALHOSYKFSA-N

Note

  • A derivative of the rauwolfia alkaloid AJMALINE. It is an anti-arrhythmia agent, but may cause liver damage.

Molecular Formula

  • C23-H33-N2-O2

Molecular Weight

  • 369.5257
 

Classification Codes

  • Anti-Arrhythmia Agents
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Prajmaline
  • Prajmalium

MeSH Heading

  • Prajmaline

Synonyms

  • (17R,21-alpha)-17,21-Dihydroxy-4-propylajmalanium
  • N(sup 4)-Propylajmalinium
  • N-Propylajmaline
  • N-Propylajmalinium
  • Prajmaline
  • Prajmalium
  • Prajmalum
  • UNII-75934UD4GJ

Systematic Name

  • Ajmalanium, 17,21-dihydroxy-4-propyl-, (17R,21-alpha)-

Registry Numbers

CAS Registry Number

  • 35080-11-6

FDA UNII

  • 75934UD4GJ

System Generated Number

  • 0035080116

Structure Descriptors

InChI

1S/C23H33N2O2/c1-4-10-25-17-11-14(13(5-2)22(25)27)19-18(25)12-23(21(19)26)15-8-6-7-9-16(15)24(3)20(17)23/h6-9,13-14,17-22,26-27H,4-5,10-12H2,1-3H3/q+1/t13-,14-,17-,18-,19-,20-,21+,22+,23+,25-/m0/s1

InChIKey

UAUHEPXILIZYCU-ALHOSYKFSA-N

Smiles

CCC[N@+]12[C@H](O)[C@@H](CC)[C@@H]3C[C@H]1[C@@H]4N(C)c5ccccc5[C@]46C[C@H]2[C@H]3[C@H]6O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 3400ug/kg (3.4mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Chemical and Pharmaceutical Bulletin. Vol. 22, Pg. 2329, 1974.
mouse LD50 oral 65500ug/kg (65.5mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: ATAXIA
Chemical and Pharmaceutical Bulletin. Vol. 22, Pg. 2329, 1974.
rat LD50 intravenous 1400ug/kg (1.4mg/kg) CARDIAC: OTHER CHANGES Pharmazie. Vol. 31, Pg. 36, 1976.